Gene Report

Basic Info
Approved Symbol SSTR5
Approved Name somatostatin receptor 5
Location 16p13.3
Position chr16:1078781-1080142, 1
External Links HGNC: 11334
Entrez Gene: 6755
Ensembl: ENSG00000162009
UCSC: uc021taf.1
No. of Studies 2 (Positive: 1; Negative: 1; trend: 0)
Overlap with SZ? NO
Overlap with MDD? YES
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Nyegaard, M.,2002 Other variant: SSTR5_ -2134delT, SSTR5_A-1665G, SSTR5_C155T, SSTR5_C325T, SSTR5_C633T, SSTR5_C-801G, SSTR5_T-2187G, SSTR5_T-461C, SSTR5_G573A, SSTR5_C1004T, SSTR5_C142A Our results may indicate that the SSTR5 gene is involved in the etiology of BPAD or may exist in linkage disequilibrium with a susceptibility gene close to SSTR5. Positive Comment on Study
Yosifova, A.,2009 SNP: rs169068 No SNP of this gene had significant association with BD in our population. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 16)

GO terms by PBA (count: 4)

GO terms by database search (count: 12)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 1)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 5)

Related other genetic factors
Gene related SNPs (count: 1)

Literature-origin SNPs (count: 1)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 11)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 0)

Overlap with MDD from candidate gene intersection analysis (count: 1)

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Region: chr16:1078781..1080142 View in gBrowse
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