Gene Report

Basic Info
Approved Symbol BDKRB2
Symbol Alias BK-2
Approved Name bradykinin receptor B2
Location 14q32.1-q32.2
Position chr14:96204679-96244166, 1
External Links HGNC: 1030
Entrez Gene: 624
Ensembl: ENSG00000168398
UCSC: uc010avm.1
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Gratacos, M.,2009 SNP: rs945032 In summary, we have identified a functional variant in the BDKRB2 gene strongly associated (odd ratios between 1.65 and 3.06) to several psychiatric disorders, mainly panic disorder, substance abuse and bipolar disorder. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 25)

GO terms by PBA (count: 3)

GO terms by database search (count: 22)

Gene related KEGG pathways (count: 4)

KEGG pathways by PBA (count: 1)

KEGG pathways by database search (count: 3)

Gene related BioCarta pathways (count: 1)

BioCarta pathways by PBA (count: 0)

BioCarta pathways by database search (count: 1)

Gene related interactors from protein-protein interactions data in HPRD (count: 11)

Related other genetic factors
Gene related SNPs (count: 4)

Literature-origin SNPs (count: 1)

LD-proxies (count: 3)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr14:96204679..96244166 View in gBrowse
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