Gene Report

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Basic Info

Approved Symbol	ATRNL1
Symbol Alias	KIAA0534, FLJ45344, ALP
Approved Name	attractin-like 1
Location	10q26
Position	chr10:115093365-115948992, 1
External Links	HGNC: 29063 Entrez Gene: 26033 Ensembl: ENSG00000107518 UCSC: uc001lcg.3
No. of Studies	1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Xu, W., 2014	SNP: rs17093782	The SNP within or near this gene did not achieve genome-wide significance.	Negative	Comment on Study

Gene functional annotation

Gene related GO terms (count: 5)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0004872	receptor activity	molecular function	IEA	19
GO:0007275	multicellular organismal development	biological process	IEA	24
GO:0016021	integral component of membrane	cellular component	IEA	219
GO:0030246	carbohydrate binding	molecular function	IEA	6

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0007186	G-protein coupled receptor signaling pathway	biological process	IEA	64

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 1)

Gene	Interactor	Interactor in BDgene?	Experiment Type	PMID
ATRNL1	MC4R	NO	in vitro;yeast 2-hybrid	14531729

Related other genetic factors

Gene related SNPs (count: 1)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs17093782	chr10:115917994 - 115917994(1)	intron_variant; non_coding_transcript_variant	1(0/1/0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
Chr 10	chr10:0-133797422	3 (0/2/1)
10q25-q26	chr10:104000000-133797422	2 (0/0/2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

View in gBrowse

Region: chr10:115093365..115948992 View in gBrowse