Gene Report

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Basic Info

Approved Symbol	OR2Y1
Approved Name	olfactory receptor, family 2, subfamily Y, member 1
Location	5q35
Position	chr5:180739042-180740099, -1
External Links	HGNC: 14837 Entrez Gene: 134083 Ensembl: ENSG00000174339 UCSC: uc003mmf.1
No. of Studies	1 (Positive: 0; Negative: 0; trend: 1)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
McQuillin, A.,2011		Gene related CNV occurred in two or more cases but not in controls.	Trend	Comment on Study

Gene functional annotation

Gene related GO terms (count: 6)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0005886	plasma membrane	cellular component	TAS	360
GO:0016021	integral component of membrane	cellular component	IEA	219

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0004984	olfactory receptor activity	molecular function	IEA	5
GO:0004930	G-protein coupled receptor activity	molecular function	IEA	26
GO:0050911	detection of chemical stimulus involved in sensory perception of smell	biological process	IEA	5
GO:0007186	G-protein coupled receptor signaling pathway	biological process	IEA	64

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in BDgene	Brief Description
hsa04740	Olfactory transduction	11

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_McQuillin[2011]_8	chr5:180098728-180099664 (NCBI Build 36 (hg18))	937

Gene related other variants (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
Chr 5	chr5:0-181538259	3 (0/2/1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr5:180739042..180740099 View in gBrowse