Gene Report

Basic Info
Approved Symbol GABBR2
Previous Symbol GPR51
Symbol Alias HG20, GABABR2, GPRC3B
Approved Name gamma-aminobutyric acid (GABA) B receptor, 2
Previous Name G protein-coupled receptor 51
Location 9q22.1-q22.3
Position chr9:98288082-98709197, -1
External Links HGNC: 4507
Entrez Gene: 9568
Ensembl: ENSG00000136928
UCSC: uc004ays.3
No. of Studies 2 (Positive: 0; Negative: 2; trend: 0)
Overlap with SZ? NO
Overlap with MDD? YES
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Xu, W., 2014 SNP: rs7864144 The SNP within or near this gene did not achieve genome-wide significance. Negative Comment on Study
Ollila, H. M.,2009 SNP: rs3802477 It showed no evidence for association with BPI in our study. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 13)

GO terms by PBA (count: 5)

GO terms by database search (count: 8)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 1)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 6)

Related other genetic factors
Gene related SNPs (count: 5)

Literature-origin SNPs (count: 2)

LD-proxies (count: 3)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 0)

Overlap with MDD from candidate gene intersection analysis (count: 1)

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Region: chr9:98288082..98709197 View in gBrowse
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