Gene Report

Basic Info
Approved Symbol TSHR
Symbol Alias LGR3
Approved Name thyroid stimulating hormone receptor
Location 14q24-q31
Position chr14:80954989-81146302, 1
External Links HGNC: 12373
Entrez Gene: 7253
Ensembl: ENSG00000165409
UCSC: uc001xvd.1
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Noor A., 2014 A duplication of 5 (or 6, depending on isoform) out of 10 coding exons of the thyroid stimulating hormone receptor gene, TSHR, was identified in another BD case. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 15)

GO terms by PBA (count: 4)

GO terms by database search (count: 11)

Gene related KEGG pathways (count: 2)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 2)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 18)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr14:80954989..81146302 View in gBrowse
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