Gene Report

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Basic Info

Approved Symbol	OR1B1
Symbol Alias	OR9-B
Approved Name	olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene)
Location	9q33.2
Position	chr9:122628579-122629573, -1
External Links	HGNC: 8181 Entrez Gene: 347169 Ensembl: ENSG00000171484 UCSC: uc011lyz.2
No. of Studies	1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Xu, W., 2014	SNP: rs17649473	The SNP within or near this gene did not achieve genome-wide significance.	Negative	Comment on Study

Gene functional annotation

Gene related GO terms (count: 8)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0016021	integral component of membrane	cellular component	IBA	219
GO:0005886	plasma membrane	cellular component	TAS	360

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0004930	G-protein coupled receptor activity	molecular function	IEA	26
GO:0004984	olfactory receptor activity	molecular function	IEA	5
GO:0050911	detection of chemical stimulus involved in sensory perception of smell	biological process	IEA	5
GO:0050907	detection of chemical stimulus involved in sensory perception	biological process	IBA	2
GO:0007186	G-protein coupled receptor signaling pathway	biological process	IBA	64
GO:0004888	transmembrane signaling receptor activity	molecular function	IBA	10

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in BDgene	Brief Description
hsa04740	Olfactory transduction	11

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 1)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs17649473	chr9:122629596 - 122629596(1)	intron_variant; non_coding_transcript_variant; upstream_gene_variant	1(0/1/0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
Chr 9	chr9:0-138394717	3 (0/3/0)
9q33	chr9:114900000-127500000	1 (0/0/1)
9q32-q33	chr9:112100000-127500000	1 (0/0/1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr9:122628579..122629573 View in gBrowse