BDgene

BD & MDD shared other variants from cross-disorder studies

Total result: 106

Variant Name Related Gene No. of Studies (Positive/Trend/Negative) for BD No. of Studies for MDD Overlap with MDD
Statistical Results Description Result Category Reference
5HTTLPR SLC6A4 41(12/0/29) 12
two-tailed P-value=0.649, X2=0.207, df=1 for MDD...... two-tailed P-value=0.649, X2=0.207, df=1 for MDD patients, P-value=0.483, X2=0.491, df=1 for combined patients More... the frequency of the 5' regulatory variant alleles did not ...... the frequency of the 5' regulatory variant alleles did not differ between controls and combined patients or MDD patients More... Negative Hoehe, M. R., 1998
Association analysis:unipolar vs. control, X2 =...... Association analysis:unipolar vs. control, X2 = 11.760, d.f. = 2, P-value = 0.003 for genotypes; P-value = 0.001 for alleles. More... Significant associations were found in MDD. Significant associations were found in MDD. Positive Hauser, J.,2003
BDNF Val66Met BDNF 21(11/0/10) 1
Association analysis:genotype P-value = 0.598, allele P-val...... Association analysis:genotype P-value = 0.598, allele P-value = 0.497 More... No significant association was observed in MDD. No significant association was observed in MDD. Negative Hong, C. J.,2003
SLC6A4 intron2 VNTR SLC6A4 16(4/0/12) 6
X2 (df=2)=0.14, P-value = 0.14 in European/Ameri...... X2 (df=2)=0.14, P-value = 0.14 in European/American populations. X2 (df=2)=2.6, P-value = 0.11 in the Asian population More... None of the three alleles (Stin2.9, Stin2.10, Stin2.12) wer...... None of the three alleles (Stin2.9, Stin2.10, Stin2.12) were associated with MDD. More... Negative Lotrich, F. E., 2004
Association analysis:allele P-value > 0.05, genotype P-valu...... Association analysis:allele P-value > 0.05, genotype P-value > 0.05 More... No significant association was observed in MDD. No significant association was observed in MDD. Negative Mellerup, E.,2001
COMT Val158Met COMT 14(2/0/12) 2
Chi-square tests:genotype frequency,chi square = 1.2, df = ...... Chi-square tests:genotype frequency,chi square = 1.2, df = 2, p > 0.05;allele frequencies,chi square = 1.2, df = 1, p > 0.05. More... No significant differences were found in unipolar groups. No significant differences were found in unipolar groups. Negative Kunugi, H.,1997(b)
Logistic regression analyses, for MDD compared to controls,...... Logistic regression analyses, for MDD compared to controls, genotype:X2wald=4.39, df=2, P-value = 0.11;allele:X2wald=1.78, df=1, P-value = 0.18 More... No association emerged between MDD cases and control subjec...... No association emerged between MDD cases and control subjects.But an association was found between the high-activity COMT Val allele, particularly the COMT Val/Val genotype and EO-MDD. More... Negative Massat, I.,2005
MTHFR C677T MTHFR 13(5/0/8) 6
T vs. C: P-value Q-test=0.19, Fixed effects OR (95% CI)=1.1...... T vs. C: P-value Q-test=0.19, Fixed effects OR (95% CI)=1.15 [0.97-1.36], Random effects OR (95% CI)=1.14 [0.92-1.41] in all; P-value Q-test=0.05, Fixed effects OR (95% CI)=1.02 [0.77-1.35], Random effects OR (95% CI)=1.04 [0.59-1.89] in Caucasians; P-value Q-test=0.55, Fixed effects OR (95% CI)=1.23 [1.00-1.52], Random effects OR (95% CI)=1.23 [1.00-1.52] in East Asians; TT vs. CC: P-value Q-test=0.41, Fixed effects OR (95% CI)=1.27 [0.86-1.84], Random effects OR (95% CI)=1.28 [0.88-1.86] in all; P-value Q-test=0.5, Fixed effects OR (95% CI)=1.04 [0.57-1.90], Random effects OR (95% CI)=1.05 [0.51-2.17] in Caucasians; P-value Q-test=0.17, Fixed effects OR (95% CI)=1.44 [0.90-2.31], Random effects OR (95% CI)=1.45 [0.90-2.33] in East Asians; TT vs. (TC + CC): P-value Q-test=0.68, Fixed effects OR (95% CI)=1.17 [0.83-1.65], Random effects OR (95% CI)=1.17 [0.83-1.66] in all; P-value Q-test=0.97, Fixed effects OR (95% CI)=0.97 [0.54-1.72], Random effects OR (95% CI)=0.97 [0.54-1.72] in Caucasians; P-value Q-test=0.21, Fixed effects OR (95% CI)=1.30 [0.84-2.01], Random effects OR (95% CI)=1.31 [0.85-2.02] in East Asians; (TT + TC) vs. CC: P-value Q-test=0.08, Fixed effects OR (95% CI)=1.21 [0.96-1.53], Random effects OR (95% CI)=1.20 [0.85-1.70] in all; P-value Q-test=0.04, Fixed effects OR (95% CI)=1.05 [0.72-1.53], Random effects OR (95% CI)=1.12 [0.41-3.08] in Caucasians; P-value Q-test=0.31, Fixed effects OR (95% CI)=1.32 [0.98-1.77], Random effects OR (95% CI)=1.32 [0.98-1.77] in East Asians More... In depression, the pattern of results in terms of heterogen...... In depression, the pattern of results in terms of heterogeneity and association is similar to that of bipolar disorder, overall and in east Asians. In Caucasians, there was no association between C677T and depression. It seems that the MTHFR C677T polymorphism plays no role in the development of affective disorders. More... Positive Zintzaras, E., 2006
chi-square P-value=0.84, X2=0, OR=1.1 (0.51-2.31...... chi-square P-value=0.84, X2=0, OR=1.1 (0.51-2.31) More... there was no significantly increased frequency of homozygos...... there was no significantly increased frequency of homozygosity for the T677 allele in any of the diagnostic groups, compared to the controls. More... Negative Kunugi, H., 1998
MAOA promoter VNTR MAOA 9(0/0/9) 2
Meta analysis:for Asian, OR(95%CI)=1.23(1.02-1.47), P-value...... Meta analysis:for Asian, OR(95%CI)=1.23(1.02-1.47), P-value(Q)=0.03, P-value(Z)=0.08;for Caucasian, OR(95%CI)=1.12(0.92-1.36), P-value(Q)=0.24, P-value(Z)=0.62 More... Our meta-analysis showed a significant association between ...... Our meta-analysis showed a significant association between uVNTR and MDD for the Asian group. More... Positive Fan, M.,2010
Chi square tests:allele,chi square = 0, df = 1, p = 0.84 Chi square tests:allele,chi square = 0, df = 1, p = 0.84 No significant differences were found in unipolar groups. No significant differences were found in unipolar groups. Negative Kunugi, H.,1999(b)
DRD3 Ser9Gly DRD3 9(2/0/7) 2
chi square tests:all P-value >0.05 chi square tests:all P-value >0.05 No significant differences were found in unipolar groups. No significant differences were found in unipolar groups. Negative Manki, H.,1996
Association analysis:Conditional logistic regression, all P...... Association analysis:Conditional logistic regression, all P-value > 0.05 More... No significant association was observed in MDD. No significant association was observed in MDD. Negative Massat, I.,2002(b)
HTR2A C102T HTR2A 8(0/0/8) 1
Association analysis:z test, allele 205bp, P-value > 0.05 Association analysis:z test, allele 205bp, P-value > 0.05 No significant association was observed in MDD. No significant association was observed in MDD. Negative Massat, I.,2000
MAOA (CA)n MAOA 8(5/0/3) 3
Chi square test:chi square = 3.349, 3 df, P-value = 0.34 Chi square test:chi square = 3.349, 3 df, P-value = 0.34 No significant differences were found when the control alle...... No significant differences were found when the control allele frequencies were compared with those in unipolar groups. More... Negative Furlong, R. A.,1999(a)
P-value=0.924, X2=5.135, 11 d.f. P-value=0.924, X2=5.135, 11 d.f. There was no overall or specific association between MAO al...... There was no overall or specific association between MAO alleles and either bipolar or unipolar patients for any of the markers before corrections for multiple tests. More... Negative Muramatsu, T., 1997
DRD4 exon3 VNTR DRD4 8(1/0/7) 3
chi square tests:chi square = 6.49, df = 1, P = 0.011 for a...... chi square tests:chi square = 6.49, df = 1, P = 0.011 for allele 4; chi square = 5.54, df = 1. P = 0.019 for allele 5. More... There was a significant difference between patients with un...... There was a significant difference between patients with unipolar disorder and controls. More... Positive Manki, H.,1996
The pooled analyses:for 2 repeat allele, OR(95%CI)=1.73(1.2...... The pooled analyses:for 2 repeat allele, OR(95%CI)=1.73(1.29-2.32), P-value = 0.003;for 4 repeat allele, OR(95%CI)=0.88(0.72-1.09), P-value = 0.24;for 7 repeat allele, OR(95%CI)=0.70(0.53-0.94), P-value = 0.02;for short allele, OR(95%CI)=1.23(0.89-1.70), P-value = 0.22 More... Significant association was found in 2 repeat allele and 7 ...... Significant association was found in 2 repeat allele and 7 repeat allele for MDD(P<0.001). More... Positive Lopez Leon, S.,2005
TPH1 A218C TPH1 6(2/0/4) 2
Association analysis:Chi square tests:alleles, X2 Association analysis:Chi square tests:alleles, X2= 0.205, P-value = 0.65; genotypes X2= 0.55, P-value = 0.757 More... No significant association was observed in MDD. No significant association was observed in MDD. Negative Souery, D.,2001
Association analysis:chi sauqre test, P-value > 0.05 Association analysis:chi sauqre test, P-value > 0.05 No significant association was observed in MDD. No significant association was observed in MDD. Negative Serretti, A.,2001(a)
5-HTT intron 2 VNTR SLC6A4 5(1/0/4) 3
Fisher’s exact test, P-value>0.999 between controls and M...... Fisher’s exact test, P-value>0.999 between controls and MDD patients of allele 9; P-value=0.453 between controls and combined patients of allele 9 More... the frequency of the second intron allele 9 did not differ ...... the frequency of the second intron allele 9 did not differ between controls and combined patients nor between controls and MDD patients More... Negative Hoehe, M. R., 1998
genotypes bearing the 9 allele in the out-patient, non lith...... genotypes bearing the 9 allele in the out-patient, non lithium unipolars: P-value=0.041, Fisher’s exact test, one-tail; P-value=0.056, Fisher’s exact test, one-tail, when compared against the lithium clinic unipolar probands. More... The frequency of the rare 9 allele was greater in unipolars...... The frequency of the rare 9 allele was greater in unipolars (0.04) than controls (0.02) although comparing the combined sample of unipolars against controls reveals no statistically significant difference in allele or genotype distributions. However, the frequency was greater in the out-patient, non-lithium unipolars (0.08) and the overrepresentation of genotypes bearing the 9 allele amongst these probands achieves statistical signifiance when compared against the controls and approaches significance when compared against the lithium clinic unipolar probands. More... Positive Rees, M., 1997
TH intron 1 tetranucleotide repeat TH 5(0/0/5) 2
Fisher's exact test:all P-value >0.05 Fisher's exact test:all P-value >0.05 No significant differences were found in unipolar groups. No significant differences were found in unipolar groups. Negative Souery, D.,1996(a)
For unipolar vs. control: alleles, chi squre = 4.33, 4 df, ...... For unipolar vs. control: alleles, chi squre = 4.33, 4 df, P-value = 0.36; genotypes, chi squre = 17.69, 14 df, P-value = 0.22;For meta analysis:P-value>0.05. More... No significant differences were found in unipolar groups. No significant differences were found in unipolar groups. Negative Furlong, R. A.,1999(c)
DRD2 S311C DRD2 5(0/0/5) 3
Association analysis:chi sauqre test, P-value > 0.05 Association analysis:chi sauqre test, P-value > 0.05 No significant association was observed in MDD. No significant association was observed in MDD. Negative Serretti, A.,2000(a)
chi square tests:all P-value >0.05 chi square tests:all P-value >0.05 No significant differences were found in unipolar groups. No significant differences were found in unipolar groups. Negative Manki, H.,1996
HTR2A -1438A/G HTR2A 4(1/0/3) 1
Association analysis:P-value > 0.05. Association analysis:P-value > 0.05. No significant association was observed in MDD. No significant association was observed in MDD. Negative Bonnier, B.,2002
SERT VNTR SLC6A4 4(2/0/2) 2
chi square tests:allele 12, P-value = 0.011 chi square tests:allele 12, P-value = 0.011 Significant differences were found in unipolar groups. Significant differences were found in unipolar groups. Positive Liu, W,1999
chi square test:allele 12, chi 2 p = 0.18 chi square test:allele 12, chi 2 p = 0.18 No significant differences were found in major depression g...... No significant differences were found in major depression groups. More... Negative Collier, D. A.,1996
ACE insertion/deletion ACE 4(2/0/2) 2
Association analysis:Alleles, X2=1.228, 1 df, P-...... Association analysis:Alleles, X2=1.228, 1 df, P-value = 0.27;Genotypes, X2= 1.281, 2 df, P-value = 0.57 More... No significant association was observed in MDD. No significant association was observed in MDD. Negative Furlong, R. A.,2000
chi square test:BPAD: P-value < 0.05 for genotype DD/(ID+II...... chi square test:BPAD: P-value < 0.05 for genotype DD/(ID+II);P-value < 0.03 for allele More... The D allele was significantly more frequent in the patient...... The D allele was significantly more frequent in the patients with major depression than in the controls, and the DD genotype was significantly more frequent in the patients with major depression than in the controls. More... Positive Arinami, T.,1996
TH TaqI Polymorphism TH 4(2/0/2) 1
Fisher's exact test:genotype, Fi = 9.99; p = 0.002;homozygo...... Fisher's exact test:genotype, Fi = 9.99; p = 0.002;homozygotes-heterozygotes distribution,Fi = 6.28; p = 0.01 More... There was a significant difference between patients with un...... There was a significant difference between patients with unipolar disorder and controls. More... Positive Souery, D.,1996(a)
MTHFR A1298C MTHFR 4(3/0/1) 1
X2 test:for Md, X2=6.65, genotype P-...... X2 test:for Md, X2=6.65, genotype P-value = 0.036 More... Significant associations were found in MD patients. Significant associations were found in MD patients. Positive Reif, A.,2005
rs6195 NR3C1 3(0/0/3) 1
X2 test:allele, P-value > 0.05;the Fisher exact ...... X2 test:allele, P-value > 0.05;the Fisher exact test:genotype, P-value > 0.05 More... No significant association was observed. No significant association was observed. Negative Szczepankiewicz, A.,2011
HTR2C Cys23Ser HTR2C 3(3/0/0) 1
Association analysis:Logistic regression, chi square= 7.34,...... Association analysis:Logistic regression, chi square= 7.34, df 1, P-value = 0.006 More... Significant associations were found in MDD patients. Significant associations were found in MDD patients. Positive Lerer, B.,2001
BDNF (GT)n BDNF 3(2/0/1) 1
Allele distribution:in Bonn sample, for MDD, P-value = 0.02...... Allele distribution:in Bonn sample, for MDD, P-value = 0.028;in Munich sample, for MDD, P-value = 0.084 More... Significant association was found in Bonn sample. Significant association was found in Bonn sample. Positive Schumacher, J.,2005
TH PstI Polymorphism TH 3(0/0/3) 1
For Cambridge unipolar vs. control: alleles, chi squre = 3....... For Cambridge unipolar vs. control: alleles, chi squre = 3.946, 1 df, P-value = 0.047; genotypes, chi squre = 4.436, 2 df, P-value = 0.11; for Edinburgh unipolar vs. control: alleles, chi squre = 0.661, 1df, P-value = 0.42; genotypes, chi squre = 2.274, 2 df, P-value = 0.32. More... Significant differences were found in Cambridge unipolar gr...... Significant differences were found in Cambridge unipolar groups. More... Positive Furlong, R. A.,1999(c)
WFS1 G576S WFS1 3(0/0/3) 1
Association analysis:chi sauqre test, allele P-value = 0.26 Association analysis:chi sauqre test, allele P-value = 0.26 No significant association was observed in MDD. No significant association was observed in MDD. Negative Ohtsuki, T.,2000
WFS1 H611R WFS1 3(0/0/3) 1
Alleles:chi square = 2.37,1df,P-value = 0.12;Genotypes:chi ...... Alleles:chi square = 2.37,1df,P-value = 0.12;Genotypes:chi square = 2.40,2df,P-value = 0.30 More... No significant differences were found in unipolar groups. No significant differences were found in unipolar groups. Negative Furlong, R. A.,1999(b)
MAOA T941G MAOA 3(2/0/1) 2
Meta analysis:for Asian, OR(95%CI)=0.78(0.53-1.13), P-value...... Meta analysis:for Asian, OR(95%CI)=0.78(0.53-1.13), P-value(Q)=0.19, P-value(Z)=0.84;for Caucasian, OR(95%CI)=1.16(0.89-1.52), P-value(Q)=0.27, P-value(Z)=0.82 More... No significant association was observed. No significant association was observed. Negative Fan, M.,2010
no P-value was given no P-value was given No significant differences in the allele or genotype distri...... No significant differences in the allele or genotype distribution were observed between the control group and any disease group. More... Negative Sasaki, T., 1998
MAOB (GT)n MAOB 3(1/0/2) 2
P-value=0.109, X2=16.954, 11 d.f. P-value=0.109, X2=16.954, 11 d.f. There was no overall or specific association between MAO al...... There was no overall or specific association between MAO alleles and either bipolar or unipolar patients for any of the markers before corrections for multiple tests. More... Negative Muramatsu, T., 1997
Association analysis:z test, allele 116bp, P-value > 0.05 Association analysis:z test, allele 116bp, P-value > 0.05 No significant association was observed in MDD. No significant association was observed in MDD. Negative Lin, S.,2000
DDC 1bp del DDC 3(2/0/1) 2
Statistical analysis of the 4-bp deletion: all P-values > 0...... Statistical analysis of the 4-bp deletion: all P-values > 0.05. More... No significant association was found between the 4-bp delet...... No significant association was found between the 4-bp deletion and Unipolar patients. More... Negative Borglum, A. D.,1999
Association analysis:Fisher's exact test, P-value > 0.05 Association analysis:Fisher's exact test, P-value > 0.05 No significant association was observed in MDD. No significant association was observed in MDD. Negative Jahnes, E.,2002
DDC 4bp del DDC 3(1/0/2) 2
Statistical analysis of the 4-bp deletion: all P-values > 0...... Statistical analysis of the 4-bp deletion: all P-values > 0.05. More... No significant association was found between the 4-bp delet...... No significant association was found between the 4-bp deletion and Unipolar patients. More... Negative Borglum, A. D.,1999
Association analysis:Fisher's exact test, P-value > 0.05 Association analysis:Fisher's exact test, P-value > 0.05 No significant association was observed in MDD. No significant association was observed in MDD. Negative Jahnes, E.,2002
GPR50 delta502-505 GPR50 3(1/0/2) 2
Single marker association:for MDD, allele P-value = 0.011(a...... Single marker association:for MDD, allele P-value = 0.011(all), P-value = 0.48(male), P-value = 0.0064(female) More... Association was observed in MDD and MDD(female). Association was observed in MDD and MDD(female). Positive Thomson, P. A.,2005(b)
X2 goodness of fit test:P-value > 0.05 X2 goodness of fit test:P-value > 0.05 No significant association was observed. No significant association was observed. Negative Macintyre, D. J.,2010
ADCY9 2316A>G ADCY9 2(1/0/1) 1
Association analysis:X2 test, genotype P-value =...... Association analysis:X2 test, genotype P-value = 0.389, allele P-value = 0.287 More... No significant association was observed in MDD. No significant association was observed in MDD. Negative Toyota, T.,2002
ADCY9 (TTTA)n ADCY9 2(1/0/1) 1
Association analysis:X2 test, genotype P-value =...... Association analysis:X2 test, genotype P-value = 0.881, allele P-value = 0.691 More... No significant association was observed in MDD. No significant association was observed in MDD. Negative Toyota, T.,2002
HTR6 267C/T HTR6 2(1/0/1) 1
Chi square test:genotype P-value = 0.372;allele P-value = 0...... Chi square test:genotype P-value = 0.372;allele P-value = 0.628 More... No significant differences were found in major depression g...... No significant differences were found in major depression groups. More... Negative Hong, C. J.,1999
COMT H/L COMT 2(1/0/1) 1
X2 = 5.72, df = 1, P-value = 0.012; OR=2.19, 95%...... X2 = 5.72, df = 1, P-value = 0.012; OR=2.19, 95%CI=1.19-4.03, Lod score=0.340 More... Patients with depressive disorders exhibited a significantl...... Patients with depressive disorders exhibited a significantly higher rate of genotypes with the COMTL allele than healthy controls, which was not the case in patients with bipolar disorders. The presence of the COMTL allele was significantly associated with depressive disorders. More... Positive Ohara, K., 1998
TPH1 intron 7 218A/C TPH1 2(0/0/2) 1
Chi square tests:genotype,chi square = 2.2, df = 2, p = 0.3...... Chi square tests:genotype,chi square = 2.2, df = 2, p = 0.34;allele,chi square = 0.9, df = 1, p = 0.35 More... No significant differences were found in unipolar groups. No significant differences were found in unipolar groups. Negative Kunugi, H.,1999(a)
DAT 40bp repeat SLC6A3 2(0/0/2) 1
chi square tests:all P-value >0.05 chi square tests:all P-value >0.05 No significant differences were found in unipolar groups. No significant differences were found in unipolar groups. Negative Manki, H.,1996
rs1129647 GABRA1 1(1/0/0) 1
Association analysis:genotype P-value = 0.07, allele P-valu...... Association analysis:genotype P-value = 0.07, allele P-value = 0.08 More... No significant association was observed. No significant association was observed. Negative Horiuchi, Y.,2004
ABCA13 exon33 H3609P ABCA13 1(0/0/1) 1
Fisher's exact test: P-value = 0.130, Odds Ratio=2.62 in MD...... Fisher's exact test: P-value = 0.130, Odds Ratio=2.62 in MDD More... No significant associations were found in SZ and MDD. No significant associations were found in SZ and MDD. Negative Knight, H. M.,2009
ABCA13 exon40 T4031A ABCA13 1(1/0/0) 1
Fisher's exact test: P-value = 0.130, Odds Ratio=2.62 in MD...... Fisher's exact test: P-value = 0.130, Odds Ratio=2.62 in MDD More... No significant associations were found in SZ and MDD. No significant associations were found in SZ and MDD. Negative Knight, H. M.,2009
ABCA13 exon52 R4590W ABCA13 1(0/0/1) 1
Fisher's exact test: P-value = 0.130, Odds Ratio=2.62 in MD...... Fisher's exact test: P-value = 0.130, Odds Ratio=2.62 in MDD More... No significant associations were found in SZ and MDD. No significant associations were found in SZ and MDD. Negative Knight, H. M.,2009
ABCA13 exon52 T4550A ABCA13 1(1/0/0) 1
Fisher's exact test: P-value = 0.63, Odds Ratio=1.18 in MDD...... Fisher's exact test: P-value = 0.63, Odds Ratio=1.18 in MDD More... No significant associations were found in SZ and MDD. No significant associations were found in SZ and MDD. Negative Knight, H. M.,2009
ABCA13 exon54 R4728X ABCA13 1(0/0/1) 1
Fisher's exact test: P-value = 0.600, Odds Ratio=1.21 in MD...... Fisher's exact test: P-value = 0.600, Odds Ratio=1.21 in MDD More... No significant associations were found in SZ and MDD. No significant associations were found in SZ and MDD. Negative Knight, H. M.,2009
ABCA13 exon57 R4843C ABCA13 1(0/0/1) 1
Fisher's exact test: P-value = 0.630, Odds Ratio=1.02 in MD...... Fisher's exact test: P-value = 0.630, Odds Ratio=1.02 in MDD More... No significant associations were found in MDD. No significant associations were found in MDD. Negative Knight, H. M.,2009
SCYA2 A-2518G CCL2 1(1/0/0) 1
No genotypic or allelic association for the A-2518G polymor...... No genotypic or allelic association for the A-2518G polymorphism of SCYA2 was found considering MDD cases and controls. The present preliminary results may represent a biological discriminative influence between mood disorder subtypes. More... Negative Altamura, A. C., 2010
HTR4 IVS1+15T/C HTR4 1(0/0/1) 1
Association analysis:Fisher's exact test, genotype P-value ...... Association analysis:Fisher's exact test, genotype P-value = 0.47, allele P-value = 0.69, OR=0.4OR(95%CI)=0.1-3.4 More... No significant association was observed in MDD. No significant association was observed in MDD. Negative Ohtsuki, T.,2002
HTR4 IVS3+63C/T HTR4 1(0/0/1) 1
Association analysis:Fisher's exact test, genotype P-value ...... Association analysis:Fisher's exact test, genotype P-value = 0.8, allele P-value = 0.84, OR=0.9OR(95%CI)=0.4-2.0 More... No significant association was observed in MDD. No significant association was observed in MDD. Negative Ohtsuki, T.,2002
HTR4 IVS3+6G/A HTR4 1(0/0/1) 1
Association analysis:Fisher's exact test, genotype P-value ...... Association analysis:Fisher's exact test, genotype P-value = 1, allele P-value = 1, OR=0.97OR(95%CI)=0.5-2.0 More... No significant association was observed in MDD. No significant association was observed in MDD. Negative Ohtsuki, T.,2002
HTR4 IVS4+36T/C HTR4 1(0/0/1) 1
Association analysis:Fisher's exact test, genotype P-value ...... Association analysis:Fisher's exact test, genotype P-value = 0.49, allele P-value = 0.6, OR=1.3OR(95%CI)=0.6-2.6 More... No significant association was observed in MDD. No significant association was observed in MDD. Negative Ohtsuki, T.,2002
HTR4 SVRSNP1 HTR4 1(1/0/0) 1
Association analysis:Fisher's exact test, genotype P-value ...... Association analysis:Fisher's exact test, genotype P-value = 0.001, allele P-value = 0.0007, OR=2.1OR(95%CI)=1.4-3.2 More... Significant associations were found in MDD. Significant associations were found in MDD. Positive Ohtsuki, T.,2002
HTR4 SVRSNP2 HTR4 1(1/0/0) 1
Association analysis:Fisher's exact test, genotype P-value ...... Association analysis:Fisher's exact test, genotype P-value = 0.08, allele P-value = 0.68, OR=0.2OR(95%CI)=0.5-2.6 More... No significant association was observed in MDD. No significant association was observed in MDD. Negative Ohtsuki, T.,2002
HTR4 SVRSNP3 HTR4 1(1/0/0) 1
Association analysis:Fisher's exact test, genotype P-value ...... Association analysis:Fisher's exact test, genotype P-value = 0.09, allele P-value = 0.1, OR=1.7OR(95%CI)=0.9-3.3 More... No significant association was observed in MDD. No significant association was observed in MDD. Negative Ohtsuki, T.,2002
HTR4 SVRSNP4 HTR4 1(1/0/0) 1
Association analysis:Fisher's exact test, genotype P-value ...... Association analysis:Fisher's exact test, genotype P-value = 0.03, allele P-value = 0.15, OR=1.4OR(95%CI)=0.9-2.3 More... Significant associations were found in MDD. Significant associations were found in MDD. Positive Ohtsuki, T.,2002
HTR5A 12A/T HTR5A 1(0/0/1) 1
Association analysis:X2 test:MD vs C: X2 Association analysis:X2 test:MD vs C: X2=0.72, P-value = 0.86 More... No significant association was observed. No significant association was observed. Negative Arias, B., 2001
HTR5A 19G/C HTR5A 1(0/0/1) 1
Association analysis:X2 test:MD vs C: X2 Association analysis:X2 test:MD vs C: X2=1.05, P-value = 0.59 More... No significant association was observed. No significant association was observed. Negative Arias, B., 2001
SOD2 Ala-9Val SOD2 1(0/0/1) 1
genotypic P-value = 0.144, X2=1.561; allelic P-v...... genotypic P-value = 0.144, X2=1.561; allelic P-value = 0.199, X2=1.650 between MDD patients and controls; genotypic P-value = 0.369, X2=1.99, allelic P-value = 0.266, X2=1.24 in the combined patient group and controls More... The genotype and allele distribution of the Ala-9Val MnSOD ...... The genotype and allele distribution of the Ala-9Val MnSOD polymorphism was similar in the MDD patients and controls. Moreover, the distribution of genotypes and alleles in the Ala-9Val MnSOD polymorphism were similar in the combined patient group (MDD plus BD) and controls. More... Negative Pae, C. U., 2006
IL10 1082G/A IL10 1(0/0/1) 1
chi-square test:Comparison between MDD and CT: Genotype: X...... chi-square test:Comparison between MDD and CT: Genotype: X2=15.317, df=2, P-value < 0.001. More... The genotype distribution was significantly different betwe...... The genotype distribution was significantly different between MDD and control (P<0.001) More... Positive Clerici, M.,2009
TBX1 v14186 TBX1 1(0/0/1) 1
X2= 0.080, P-value = 0.777 for affective disord...... X2= 0.080, P-value = 0.777 for affective disorder (BP + MDD) when compared with controls More... None of the nine individual SNPs showed a positive associat...... None of the nine individual SNPs showed a positive association in the 'all affecteds' category. More... Negative Funke, B. H., 2007
CCK STR CCK 1(0/0/1) 1
Association study:P-value (genotypic)=0.323, P-value (allel...... Association study:P-value (genotypic)=0.323, P-value (allelic)=0.296 for unipolar disorder. More... No significant association was observed. No significant association was observed. Negative Hattori, E.,2002
TH 1-5 allele TH 1(0/0/1) 1
Fisher’s exact test, P-value=0.88 for UPR, P-value=1 for ...... Fisher’s exact test, P-value=0.88 for UPR, P-value=1 for BPI + UPR; Fisher’s exact test, P-value=0.32 for UPR, P-value=0.26 for BPI + UPR; Fisher’s exact test, P-value=0.66 for UPR, P-value=0.47 for BPI + UPR; Fisher’s exact test, P-value=1 for UPR, P-value=0.72 for BPI + UPR; Fisher’s exact test, P-value=0.54 for UPR, P-value=0.8 for BPI + UPR; Fisher’s exact test, P-value=0.79 for UPR, P-value=0.72 for BPI + UPR; Fisher’s exact test, P-value=0.91 for UPR, P-value=0.85 for BPI + UPR More... For the TH polymorphism, the '1,2' genotype was more freque...... For the TH polymorphism, the '1,2' genotype was more frequently observed among controls than in the patient group. However, this P value does not remain significant after applying a Bonferroni correction for multiple testing. When considering only BPI or UPR patients who were positive for family history, no significant differences were observed, either. More... Negative Oruc, L., 1997 (a)
KAT5 BanI polymorphism KAT5 1(0/0/1) 1
Association analysis:chi square test, allele P-value = 0.00...... Association analysis:chi square test, allele P-value = 0.007, chi square=7.072;genotype P-value = 0.03, chi square=6.879 More... Significant associations were found in MDD patients. Significant associations were found in MDD patients. Positive Pae, C. U.,2004(b)
COMT G/A COMT 1(1/0/0) 1
genotypic P-value = 0.32, X2=2.29, d.f.=2 for th...... genotypic P-value = 0.32, X2=2.29, d.f.=2 for the Milan sample More... COMT variants were not associated with mood disorders in ou...... COMT variants were not associated with mood disorders in our sample. More... Negative Serretti, A., 2006
CRHR2 1047G/A CRHR2 1(0/0/1) 1
Association analysis:X2 test, genotype P-value =...... Association analysis:X2 test, genotype P-value = 0.03, allele P-value = 0.04 More... Significant associations were found in MDD. Significant associations were found in MDD. Positive Villafuerte, S. M.,2002
TSPO exon4 Ala147Thr TSPO 1(0/0/1) 1
Association analysis:X2 test:genotype P-value = ...... Association analysis:X2 test:genotype P-value = 0.120;allele P-value = 0.120 More... No significant association was observed. No significant association was observed. Negative Kurumaji, A.,2001
TSPO exon4 His162Arg TSPO 1(0/0/1) 1
Association analysis:X2 test:genotype P-value = ...... Association analysis:X2 test:genotype P-value = 0.607;allele P-value = 0.854 More... No significant association was observed. No significant association was observed. Negative Kurumaji, A.,2001
MAOA A1609G MAOA 1(0/0/1) 1
no P-value was given no P-value was given No G allele was observed in any of the Japanese subjects. No G allele was observed in any of the Japanese subjects. Negative Sasaki, T., 1998
uMAOA MAOA 1(0/0/1) 1
Genotypic P-value = 0.327, allelic P-value = 0.808 Genotypic P-value = 0.327, allelic P-value = 0.808 None of the different repeat copies was found to be associa...... None of the different repeat copies was found to be associated with major depression. More... Negative Gutierrez, B., 2004
MAOA exon 8 RFLP MAOA 1(0/0/1) 1
P-value=0.426, X2=0.634, 1 d.f. P-value=0.426, X2=0.634, 1 d.f. There was no overall or specific association between MAO al...... There was no overall or specific association between MAO alleles and either bipolar or unipolar patients for any of the markers before corrections for multiple tests. More... Negative Muramatsu, T., 1997
MAOA exon 8 VNTR MAOA 1(0/0/1) 1
P-value=0.143, X2=6.863, 4 d.f. P-value=0.143, X2=6.863, 4 d.f. There was no overall or specific association between MAO al...... There was no overall or specific association between MAO alleles and either bipolar or unipolar patients for any of the markers before corrections for multiple tests. More... Negative Muramatsu, T., 1997
MAOA-Fnu MAOA 1(0/0/1) 1
Chi square test:chi square = 0.821, 1 df, P-value = 0.37 Chi square test:chi square = 0.821, 1 df, P-value = 0.37 No significant differences were found when the control alle...... No significant differences were found when the control allele frequencies were compared with those in unipolar groups. More... Negative Furlong, R. A.,1999(a)
COMT G1947A COMT 1(0/0/1) 1
P-value=0.794 for Val/Val158, P-value=0.471 for Val/Met158,...... P-value=0.794 for Val/Val158, P-value=0.471 for Val/Met158, P-value=0.256 for Met/Met158, allelic P-value=0.393 More... The Val/Met158 genotype was the most represented in all thr...... The Val/Met158 genotype was the most represented in all three groups, with higher frequencies in MDD and BD patients than incontrols, while the Met/Met158 mutated genotype was morefrequent in healthy subjects than inpatients. However, thesedifferences did not reach statistically significant values. The resultsof posthoc power analysis showed that the study was insufficientlypowered to detect the true association of G1947A(Val158-Met) variant of COMT gene with MDD and BD, if existent in these populations. More... Negative Pandolfo, G., 2015
COMT C1886G COMT 1(1/0/0) 1
P-value=0.002 for CC1886, P-value=0.025 for CG1947, P-value...... P-value=0.002 for CC1886, P-value=0.025 for CG1947, P-value=0.216 for GG1947, allelic P-value=0.003 More... Positive Pandolfo, G., 2015
MAOA LPR MAOA 1(0/0/1) 1
Association analysis:Chi square tests:alleles, X2 Association analysis:Chi square tests:alleles, X2= 0.219, P-value = 0.731 More... No significant association was observed in MDD. No significant association was observed in MDD. Negative Syagailo, Y. V.,2001
WFS1 SNP1023 WFS1 1(0/0/1) 1
Allelic association:P-value = 0.02 in MDD. Allelic association:P-value = 0.02 in MDD. Significant associations were found in MDD. Significant associations were found in MDD. Positive Koido, K.,2005
WFS1 SNP1185 WFS1 1(0/0/1) 1
Allelic association:P-value = 0.01 in MDD, Genotypic associ...... Allelic association:P-value = 0.01 in MDD, Genotypic association:P-value = 0.008 in MDD. More... Significant associations were found in MDD. Significant associations were found in MDD. Positive Koido, K.,2005
WFS1 SNP1645 WFS1 1(0/0/1) 1
Allelic association:P-value = 0.55 in MDD. Allelic association:P-value = 0.55 in MDD. No significant associations were found in MDD. No significant associations were found in MDD. Negative Koido, K.,2005
WFS1 SNP1832 WFS1 1(0/0/1) 1
Allelic association:P-value = 0.17 in MDD, Genotypic associ...... Allelic association:P-value = 0.17 in MDD, Genotypic association:P-value = 0.17 in MDD. More... No significant associations were found in MDD. No significant associations were found in MDD. Negative Koido, K.,2005
WFS1 SNP2206 WFS1 1(0/0/1) 1
Allelic association:P-value = 0.04 in MDD. Allelic association:P-value = 0.04 in MDD. Significant associations were found in MDD. Significant associations were found in MDD. Positive Koido, K.,2005
WFS1 SNP2565 WFS1 1(0/0/1) 1
Allelic association:P-value = 0.04 in MDD. Allelic association:P-value = 0.04 in MDD. Significant associations were found in MDD. Significant associations were found in MDD. Positive Koido, K.,2005
WFS1 SNP684 WFS1 1(1/0/0) 1
Allelic association:P-value = 0.007 in MDD, Genotypic assoc...... Allelic association:P-value = 0.007 in MDD, Genotypic association:P-value = 0.26 in MDD. More... Significant associations were found in MDD. Significant associations were found in MDD. Positive Koido, K.,2005
WFS1 SNP935 WFS1 1(0/0/1) 1
Allelic association:P-value = 0.19 in MDD. Allelic association:P-value = 0.19 in MDD. No significant associations were found in MDD. No significant associations were found in MDD. Negative Koido, K.,2005
DISC1 -215(TG)8-13 DISC1 1(0/0/1) 1
Genotypic P-value = 0.83, allelic P-value = 1.00 f Genotypic P-value = 0.83, allelic P-value = 1.00 f no significant differences between unipolar disorder and co...... no significant differences between unipolar disorder and controls More... Negative Arai, M., 2007
mtDNA ND4L T10652C mtDNA_ND4L 1(1/0/0) 1
Allelic association analysis:P-value(permutation)=0.026 Allelic association analysis:P-value(permutation)=0.026 Significant associations were found in MDD. Significant associations were found in MDD. Positive Rollins, B.,2009
NCAM1 2208T>G NCAM1 1(0/0/1) 1
Fisher's exact test genotypic P-value = 0.54 , allelic P-va...... Fisher's exact test genotypic P-value = 0.54 , allelic P-value = 0.92 More... For unipolar disorder, none of these polymorphisms displaye...... For unipolar disorder, none of these polymorphisms displayed nominally significant genotypic or allelic associations with the disease. More... Negative Arai, M., 2004
NCAM1 2256 2257 insATGG NCAM1 1(0/0/1) 1
Fisher's exact test genotypic P-value = 0.14 , allelic P-va...... Fisher's exact test genotypic P-value = 0.14 , allelic P-value = 0.14 More... For unipolar disorder, none of these polymorphisms displaye...... For unipolar disorder, none of these polymorphisms displayed nominally significant genotypic or allelic associations with the disease. More... Negative Arai, M., 2004
NCAM1 I621G>T NCAM1 1(0/0/1) 1
Fisher's exact test genotypic P-value = 0.28 , allelic P-va...... Fisher's exact test genotypic P-value = 0.28 , allelic P-value = 0.29 More... For unipolar disorder, none of these polymorphisms displaye...... For unipolar disorder, none of these polymorphisms displayed nominally significant genotypic or allelic associations with the disease. More... Negative Arai, M., 2004
NCAM1 IVS0-49de IG NCAM1 1(0/0/1) 1
Fisher's exact test genotypic P-value = 0.95 , allelic P-va...... Fisher's exact test genotypic P-value = 0.95 , allelic P-value = 0.89 More... For unipolar disorder, none of these polymorphisms displaye...... For unipolar disorder, none of these polymorphisms displayed nominally significant genotypic or allelic associations with the disease. More... Negative Arai, M., 2004
NCAM1 IVS4+80G>C NCAM1 1(0/0/1) 1
Fisher's exact test genotypic P-value = 0.85, allelic P-va...... Fisher's exact test genotypic P-value = 0.85, allelic P-value = 0.72 More... For unipolar disorder, none of these polymorphisms displaye...... For unipolar disorder, none of these polymorphisms displayed nominally significant genotypic or allelic associations with the disease. More... Negative Arai, M., 2004
NCAM1 IVS6+32T>C NCAM1 1(1/0/0) 1
Fisher's exact test genotypic P-value = 0.37 , allelic P-va...... Fisher's exact test genotypic P-value = 0.37 , allelic P-value = 0.90 More... For unipolar disorder, none of these polymorphisms displaye...... For unipolar disorder, none of these polymorphisms displayed nominally significant genotypic or allelic associations with the disease. More... Negative Arai, M., 2004
NCAM1 IVS7+155G>T NCAM1 1(0/0/1) 1
Fisher's exact test genotypic P-value = 0.89 , allelic P-va...... Fisher's exact test genotypic P-value = 0.89 , allelic P-value = 0.76 More... For unipolar disorder, none of these polymorphisms displaye...... For unipolar disorder, none of these polymorphisms displayed nominally significant genotypic or allelic associations with the disease. More... Negative Arai, M., 2004
DRD2 -141CIns/Del DRD2 1(0/0/1) 1
allelic P-value=0.82, X2=0.06, df=1; genotypic P...... allelic P-value=0.82, X2=0.06, df=1; genotypic P-value=0.91, X2=0.01, df=1; OR (95% CI)=1.06 (0.64-1.75) of allele 2 vs. 1, OR (95% CI)=1.03 (0.58-1.83) of 2 2 vs. 1 2 in bipolar; allelic P-value=0.72, X2=0.13, df=1; genotypic P-value=0.31, X2=1.03, df=1; OR (95% CI)=0.93 (0.63-1.38) of allele 2 vs. 1, OR (95% CI)=0.80 (0.51-1.24) of 2 2 vs. 1 2 in the combined sample More... No significant association with this polymorphism was found...... No significant association with this polymorphism was found in either disorder, not even when both groups were combined to give an 'affective disorder' group. More... Negative Furlong, R. A., 1998 (b)
DRD2 microsatellite DRD2 1(1/0/0) 1
Association analysis:Conditional logistic regression, all P...... Association analysis:Conditional logistic regression, all P-value > 0.05 More... No significant association was observed in MDD. No significant association was observed in MDD. Negative Massat, I.,2002(b)
DRD4 2-10 allele DRD4 1(0/0/1) 1
2 (218) Allele (bp): Fisher’s exact test, P-value=0.18 fo...... 2 (218) Allele (bp): Fisher’s exact test, P-value=0.18 for UPR, P-value=0.34 for BPI + UPR; 3 (266) Allele (bp): Fisher’s exact test, P-value=0.49 for UPR, P-value=0.56 for BPI + UPR; 4 (314) Allele (bp): Fisher’s exact test, P-value=0.19 for UPR, P-value=0.39 for BPI + UPR; 5 (362) Allele (bp): Fisher’s exact test, P-value=1 for UPR, P-value=0.66 for BPI + UPR; 6 (410) Allele (bp): Fisher’s exact test, P-value=1 for UPR, P-value=1 for BPI + UPR; 7 (458) Allele (bp): Fisher’s exact test, P-value=0.71 for UPR, P-value=1 for BPI + UPR; 8 (506) Allele (bp): Fisher’s exact test, P-value=0.8 for UPR, P-value=0.8 for BPI + UPR; 9 (554) Allele (bp): Fisher’s exact test, P-value=0.44 for UPR, P-value=0.18 for BPI + UPR; 10 (602) Allele (bp): Fisher’s exact test, P-value=1 for UPR, P-value=1 for BPI + UPR; Total: Fisher’s exact test, P-value=0.26 for UPR, P-value=0.27 for BPI + UPR; Homozygotes: Fisher’s exact test, P-value=0.24 for UPR, P-value=0.51 for BPI + UPR More... No significant differences were observed at the single-alle...... No significant differences were observed at the single-allele level when comparing the UPR, BPI, or combined patient populations vs. controls. More... Negative Oruc, L., 1997 (a)
DRD5 D4S615 DRD5 1(0/0/1) 1
Association analysis:CLUMP program, P-value > 0.05 Association analysis:CLUMP program, P-value > 0.05 No significant association was observed in MDD. No significant association was observed in MDD. Negative Muir, W. J.,2001
DUSP6 exon1 Leu111Val DUSP6 1(0/0/1) 1
Association analysis:allele frequencies, X2 = 0....... Association analysis:allele frequencies, X2 = 0.61, 1 df, P-value = 0.43;genotypes, P-value = 0.44 More... No significant association was observed. No significant association was observed. Negative Toyota, T.,2000
DUSP6 Leu114Val DUSP6 1(0/0/1) 1
Association analysis:chi square test, allele P-value = 0.43...... Association analysis:chi square test, allele P-value = 0.43;genotype P-value = 0.44 More... No significant association was observed in MDD. No significant association was observed in MDD. Negative Toyota, T,2000
NOS3 G894T NOS3 1(0/0/1) 1
genotypic P-value = 0.82, X2=0.41, df=2 genotypic P-value = 0.82, X2=0.41, df=2 Individual SNP association analyses by means of chi square ...... Individual SNP association analyses by means of chi square tests did not yield significant results. Similarly, no significant association between any of the polymorphisms and BD, and MD respectively, was obtained when comparing allele distributions (data not shown). More... Negative Reif, A., 2006 (b)
NOS3 Intron4 VNTR NOS3 1(0/0/1) 1
genotypic P-value = 0.88, X2=0.66, df=3 genotypic P-value = 0.88, X2=0.66, df=3 Individual SNP association analyses by means of chi square ...... Individual SNP association analyses by means of chi square tests did not yield significant results. Similarly, no significant association between any of the polymorphisms and BD, and MD respectively, was obtained when comparing allele distributions (data not shown). More... Negative Reif, A., 2006 (b)
NOS3 T-786C NOS3 1(0/0/1) 1
genotypic P-value = 0.51, X2=1.35, df=2 genotypic P-value = 0.51, X2=1.35, df=2 Individual SNP association analyses by means of chi square ...... Individual SNP association analyses by means of chi square tests did not yield significant results. Similarly, no significant association between any of the polymorphisms and BD, and MD respectively, was obtained when comparing allele distributions (data not shown). More... Negative Reif, A., 2006 (b)
NQO1 C609T NQO1 1(0/0/1) 1
chi-square test, genotypic P-value = 0.458, X2=1...... chi-square test, genotypic P-value = 0.458, X2=1.561, allelic P-value = 0.808, X2=0.059 in the MDD patients; genotypic P-value = 0.558, X2=1.158, allelic P-value = 0.460, X2=0.545 in MDD and BID patients More... There were no differences in the distribution of the genoty...... There were no differences in the distribution of the genotypes and alleles of the NQO1 C609T polymorphism between the MDD patients and the controls. The combined analysis of the MDD and BID patients did not reveal any significant association between the genotypes and allele distributions of the patients and controls. More... Negative Pae, C. U., 2007 (b)
GABRA1 -181A/G GABRA1 1(0/0/1) 1
Association analysis:genotype P-value = 0.53, allele P-valu...... Association analysis:genotype P-value = 0.53, allele P-value = 0.56 More... No significant association was observed in MDD. No significant association was observed in MDD. Negative Horiuchi, Y.,2004
GABRA1 -471T/C GABRA1 1(0/0/1) 1
Association analysis:genotype P-value = 0.99, allele P-valu...... Association analysis:genotype P-value = 0.99, allele P-value = 0.93 More... No significant association was observed in MDD. No significant association was observed in MDD. Negative Horiuchi, Y.,2004
GABRA1 IVS2-712(GT)n GABRA1 1(1/0/0) 1
Association analysis:COCAPHASE P-value = 0.29 Association analysis:COCAPHASE P-value = 0.29 No significant association was observed in MDD. No significant association was observed in MDD. Negative Horiuchi, Y.,2004
GABRA1 IVS9+76A/G GABRA1 1(0/0/1) 1
Association analysis:genotype P-value = 0.3, allele P-value...... Association analysis:genotype P-value = 0.3, allele P-value = 0.32 More... No significant association was observed in MDD. No significant association was observed in MDD. Negative Horiuchi, Y.,2004
GABRA5 3'UTR 1-8 allele GABRA5 1(1/0/0) 1
Fisher exact test, P-value=0.168 of patients, P-value=0.143...... Fisher exact test, P-value=0.168 of patients, P-value=0.143 of UP for allele 1, P-value=0.389 of patients, P-value=0.597 of UP for allele 2, P-value=0.138 of patients, P-value=0.391 of UP for allele 3, P-value=0.017 of patients, P-value=0.0065 of UP for allele 4, P-value=0.521 of patients, P-value=0.259 of UP for allele 5, P-value=0.225 of patients, P-value=0.421 for allele 6, P-value=0.657 of patients for allele 7, P-value=1 of patients, P-value=1 of UP for allele 8, P-value=0.075 of patients, P-value=0.096 for total, Homozygotes P-value=0.855 of patients, P-value=0.803 of UP More... A significant association was present in the UPR group. An ...... A significant association was present in the UPR group. An increased frequency of allele 4 was also observed in subjects with BPI disorder, but the results did not reach statistical significance. More... Positive Oruc, L., 1997 ( c)
GABRA5 (CA)n GABRA5 1(1/0/0) 1
Overall P-value=0.043, X2=15.98, df=8; UP vs. Co...... Overall P-value=0.043, X2=15.98, df=8; UP vs. Controls: X2=2.92, df=4, P-value=NS More... In the analysis between pairs of groups, a statistically si...... In the analysis between pairs of groups, a statistically significant difference was found between the BP patients and controls (P=0.004), while no such differences were observed between the groups of UP patients and controls. More... Positive Papadimitriou, G. N., 1998
GNB3 C825T GNB3 1(0/0/1) 1
Association analysis:Unipolars v. controls: genotype: X Association analysis:Unipolars v. controls: genotype: X2=0.1, 2 df, P-value = 0.97; allele: X2=0.0, 1 df, P-value = 0.93 More... No significant association was observed in MDD. No significant association was observed in MDD. Negative Kunugi, H.,2002