BDgene

Other Variant Report

Basic Info
Name SOD2 Ala-9Val
Type point mutation
Related Gene SOD2
No. of Study 1 (Positive: 0; Negative 1; Trend: 0)
Overlap with SZ? NO
Overlap with MDD? YES

Variant related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Pae, C. U., 2006 Ala/Val genotypic P-value = 0.484, X2=1.493; allelic P-value = 0.512, X2=0.431 between BD patients and controls; genotypic P-value = 0.369, X2=1.99, allelic P-value = 0.266, X2=1.24 in the combined patient group and controls
The genotype and allele distribution of the Ala-9Val MnSOD p..... More
Negative

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Pae, C. U., 2006 genotypic P-value = 0.144, X2=1.561; allelic P-value = 0.199, X2=1.650 between MDD patients and controls; genotypic P-value = 0.369, X2=1.99, allelic P-value = 0.266, X2=1.24 in the combined patient group and controls The genotype and allele distribution of the Ala-9Val MnSOD polymorphism was similar in the MDD patients and controls. Moreover, the distribution of genotypes and alleles in the Ala-9Val MnSOD polymorphism were similar in the combined patient group (MDD plus BD) and controls. Negative