BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Other Variant Report

Basic Info

Name	NQO1 C609T
Type	point mutation
Related Gene	NQO1
No. of Study	1 (Positive: 0; Negative 1; Trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	YES

Variant related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Pae, C. U., 2007 (b)	C/T		chi-square test, genotypic P-value = 0.598, X²=1.027, allelic P-value = 0.353, X²=0.862 in BID patients; genotypic P-value = 0.558, X²=1.158, allelic P-value = 0.460, X²=0.545 in MDD and BID patients	There were no differences in the distribution of the genotyp..... More There were no differences in the distribution of the genotypes and alleles of the NQO1 C609T polymorphism between the BID patients and the controls. The combined analysis of the MDD and BID patients did not reveal any significant association between the genotypes and allele distributions of the patients and controls. Less	Negative

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Pae, C. U., 2007 (b)	chi-square test, genotypic P-value = 0.458, X²=1.561, allelic P-value = 0.808, X²=0.059 in the MDD patients; genotypic P-value = 0.558, X²=1.158, allelic P-value = 0.460, X²=0.545 in MDD and BID patients	There were no differences in the distribution of the genotypes and alleles of the NQO1 C609T polymorphism between the MDD patients and the controls. The combined analysis of the MDD and BID patients did not reveal any significant association between the genotypes and allele distributions of the patients and controls.	Negative