BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

Search Gene with Disease Search Gene1 with Disease

Other Variant Report

Basic Info

Name	WFS1 H611R
Type	point mutation
Location	exon8
Related Gene	WFS1
No. of Study	3 (Positive: 0; Negative 3; Trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	YES

Variant related studies (count: 3)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Kato, T.,2003	H611R		Association analysis:Fisher's exact probability test, genotype P-value = 0.88, X²=0.17, allele P-value = 0.91	No significant association was observed in BD.	Negative
Kawamoto, T., 2004	A>G		allelic P-value = 0.16	None of the cSNPs were associated with bipolar disorder.	Negative
Furlong, R. A.,1999(b)	H611R		Alleles:chi square = 0.36,1df,P-value = 0.55;Genotypes:chi square = 2.52,2df,P-value = 0.28	No significant differences were found in bipolar groups.	Negative

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Furlong, R. A.,1999(b)	Alleles:chi square = 2.37,1df,P-value = 0.12;Genotypes:chi square = 2.40,2df,P-value = 0.30	No significant differences were found in unipolar groups.	Negative