BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Other Variant Report

Basic Info

Name	NOS3 T-786C
Type	point mutation
Related Gene	NOS3
No. of Study	1 (Positive: 0; Negative 1; Trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	YES

Variant related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Reif, A., 2006 (b)	T/C		genotypic P-value = 0.49, X²=1.42, df=2	Individual SNP association analyses by means of chi square t..... More Individual SNP association analyses by means of chi square tests did not yield significant results. Similarly, no significant association between any of the polymorphisms and BD, and MD respectively, was obtained when comparing allele distributions (data not shown). Less	Negative

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Reif, A., 2006 (b)	genotypic P-value = 0.51, X²=1.35, df=2	Individual SNP association analyses by means of chi square tests did not yield significant results. Similarly, no significant association between any of the polymorphisms and BD, and MD respectively, was obtained when comparing allele distributions (data not shown).	Negative