Gene Report

Basic Info
Approved Symbol CCK
Approved Name cholecystokinin
Name Alias prepro-cholecystokinin, "cholecystokinin triacontatriapeptide"
Location 3p22.1
Position chr3:42257825-42266207, -1
External Links HGNC: 1569
Entrez Gene: 885
Ensembl: ENSG00000187094
UCSC: uc021wwk.1
No. of Studies 2 (Positive: 0; Negative: 1; trend: 1)
Overlap with SZ? YES
Overlap with MDD? YES
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Yosifova, A.,2011 SNP: rs11129950 Suggestive association of this gene was found. Trend Comment on Study
Hattori, E.,2002 Other variant: CCK_STR No allelic or genotypic association between the CCK promoter variations and mood disorders was detected.These data suggest that the CCK promoter STR is unlikely to have a major genetic effect on the development of mood disorders in the Japanese population. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 25)

GO terms by PBA (count: 1)

GO terms by database search (count: 24)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 5)

Related other genetic factors
Gene related SNPs (count: 1)

Literature-origin SNPs (count: 1)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 1)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 3)

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 1)

Overlap with MDD from candidate gene intersection analysis (count: 0)

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Region: chr3:42257825..42266207 View in gBrowse
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