Gene Report

Basic Info
Approved Symbol KAT5
Previous Symbol HTATIP
Symbol Alias TIP60, PLIP, cPLA2, HTATIP1, ESA1, ZC2HC5
Approved Name K(lysine) acetyltransferase 5
Previous Name HIV-1 Tat interactive protein, 60kDa
Name Alias Tat interacting protein, 60kDa, "K-acetyltransferase 5"
Location 11q13
Position chr11:65711996-65719604, 1
External Links HGNC: 5275
Entrez Gene: 10524
Ensembl: ENSG00000172977
UCSC: uc001ofk.3
No. of Studies 2 (Positive: 0; Negative: 2; trend: 0)
Overlap with SZ? NO
Overlap with MDD? YES
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Pae, C. U.,2004(b) Other variant: KAT5_BanI polymorphism The polymorphism was not different between BID patients and controls in genotype and allele distribution. Negative Comment on Study
Meira-Lima, I.,2003(a) Other variant: cPLA2_BanI dimorphic site Our results failed to demonstrate that the studied PLA2 polymorphisms were associated with an increased risk for BPAD in our sample. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 33)

GO terms by PBA (count: 1)

GO terms by database search (count: 32)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 75)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 2)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 1)

Overlap with MDD from candidate gene intersection analysis (count: 1)

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Region: chr11:65711996..65719604 View in gBrowse
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