Gene Report

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Basic Info

Approved Symbol	RNF212
Previous Symbol	LOC285498
Symbol Alias	FLJ38841
Approved Name	ring finger protein 212
Previous Name	hypothetical protein LOC285498
Location	4p16.3
Position	chr4:1056250-1113562, -1
External Links	HGNC: 27729 Entrez Gene: 285498 Ensembl: ENSG00000178222 UCSC: uc003gcj.3
No. of Studies	1 (Positive: 0; Negative: 0; trend: 1)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Georgi, B., 2014	SNP: rs60035268	Putative damaging exonic variant was found within this gene.	Trend	Comment on Study

Gene functional annotation

Gene related GO terms (count: 7)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0016874	ligase activity	molecular function	IEA	16
GO:0007131	reciprocal meiotic recombination	biological process	ISS	2
GO:0016925	protein sumoylation	biological process	IEA	3
GO:0006311	meiotic gene conversion	biological process	ISS	1
GO:0051026	chiasma assembly	biological process	ISS	1
GO:0008270	zinc ion binding	molecular function	IEA	77
GO:0000795	synaptonemal complex	cellular component	ISS	1

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 1)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs60035268	chr4:1093699 - 1093699(1)	downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant; stop_gained	1(0/0/1)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
4p16.3	chr4:0-4500000	1 (1/0/0)
Chr 4	chr4:0-190214555	3 (0/3/0)
4p16	chr4:0-11300000	2 (0/1/1)
4p	chr4:0-50000000	1 (0/1/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

View in gBrowse

Region: chr4:1056250..1113562 View in gBrowse