BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Region Report

Basic Info

Region Name	7q21
Chromosome Position	chr7:77900000-98400000
No. of Studies (Positive/Negative/Trend)	4(0/2/2)

Region related studies (count: 4)

Reference	Markers	Statistical Values	Author Comments	Result Category
Greenwood, T. A.,2012	D7S2204	Linkage analysis: for BD, LOD = 1.27 Linkage analysis: for BD, LOD = 1.27	No significant linkage was found in this region. No significant linkage was found in this region.	Negative
McInnis, M. G.,2003(a)	D7S821	Linkage analysis: model II, Unconditional NPL = 0.7 Linkage analysis: model II, Unconditional NPL = 0.7	No significant linkage was found in this region. No significant linkage was found in this region.	Negative
Georgi, B., 2014	D7S518	LOD=2.99 LOD=2.99	Within the full set of 49 nuclear families the highest linka...... Within the full set of 49 nuclear families the highest linkage we observed was on 7q21 (LOD 2.99 at D7S518, BPS phenotype). More...	Trend
Lambert, D.,2005	D7S630	Linkage analysis: Multipoint MLS = 1.35(narrow), 1.07(interm...... Linkage analysis: Multipoint MLS = 1.35(narrow), 1.07(intermediate), 0.72(broad); Two point LOD score = 1.95(narrow), 2.03(intermediate), 1.47(broad); More...	Suggestive linkage was found in this region. Suggestive linkage was found in this region.	Trend

Region related genes (count: 16)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
SEMA3D	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D	7q21.11	1(1/0/0)
HEPACAM2	HEPACAM family member 2	7q21.3	1(0/0/1)
C7orf63	cilia and flagella associated protein 69	7q21.13	0
CACNA2D1	calcium channel, voltage-dependent, alpha 2/delta subunit 1	7q21-q22	2(0/0/2)
PPP1R9A	protein phosphatase 1, regulatory subunit 9A	7q21.3	1(0/0/1)
CFAP69	cilia and flagella associated protein 69	7q21.13	1(0/0/1)
CROT	carnitine O-octanoyltransferase	7q21.1	1(0/0/1)
SAMD9	sterile alpha motif domain containing 9	7q21.2	1(0/0/1)
SAMD9L	sterile alpha motif domain containing 9-like	7q21.2	1(0/0/1)
PON1	paraoxonase 1	7q21.3	2(2/0/0)
GRM3	glutamate receptor, metabotropic 3	7q21.1-q21.2	7(3/4/0)
ABCB1	ATP-binding cassette, sub-family B (MDR/TAP), member 1	7q21.12	1(1/0/0)
DYNC1I1	dynein, cytoplasmic 1, intermediate chain 1	7q21.3	1(1/0/0)
CD36	CD36 molecule (thrombospondin receptor)	7q11.2	3(2/1/0)
BET1	Bet1 golgi vesicular membrane trafficking protein	7q21.1-q22	1(1/0/0)
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	7q21	1(1/0/0)

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Region: chr7:77900000..98400000 View in gBrowse