Gene Report

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Basic Info

Approved Symbol	ITPRIPL2
Symbol Alias	FLJ22994, MGC126798, MGC126800, LOC162073
Approved Name	inositol 1,4,5-trisphosphate receptor interacting protein-like 2
Previous Name	inositol 1,4,5-triphosphate receptor interacting protein-like 2
Location	16p12.3
Position	chr16:19113932-19121629, 1
External Links	HGNC: 27257 Entrez Gene: 162073 Ensembl: ENSG00000205730 UCSC: uc002dfu.4
No. of Studies	1 (Positive: 0; Negative: 0; trend: 1)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Georgi, B., 2014	SNP: rs11074362	Putative damaging exonic variant was found within this gene.	Trend	Comment on Study

Gene functional annotation

Gene related GO terms (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0016021	integral component of membrane	cellular component	IEA	219

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 7)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs11074362	chr16:19116025 - 19116025(1)	3_prime_UTR_variant; downstream_gene_variant; intron_variant; missense_variant; NMD_transcript_variant; upstream_gene_variant	1(0/0/1)

rs_ID	Location	Functional Annotation
rs3826249	chr16:19121842 - 19121842(1)	downstream_gene_variant; intron_variant; NMD_transcript_variant; upstream_gene_variant
rs3743956	chr16:19121458 - 19121458(1)	3_prime_UTR_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant
rs3743955	chr16:19121125 - 19121125(1)	3_prime_UTR_variant; downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant
rs11859503	chr16:19117673 - 19117673(1)	3_prime_UTR_variant; downstream_gene_variant; intron_variant; NMD_transcript_variant
rs12444272	chr16:19113163 - 19113163(1)	upstream_gene_variant
rs12444250	chr16:19113092 - 19113092(1)	upstream_gene_variant

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
Chr 16	chr16:0-90338345	5 (1/3/1)
16p12	chr16:16700000-28500000	2 (1/1/0)
16p12.3-p13.1	chr16:10400000-21200000	1 (1/0/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr16:19113932..19121629 View in gBrowse