SNP Report

Basic Info

Name	rs71579374 dbSNP Ensembl
Location	chr10:74100982 - 74100982(1)
Variant Alleles	A/G
Ancestral Allele	A
Minor Allele	G
Minor Allele Frequence	3.99361E-4
Functional Annotation	3_prime_UTR_variant; intron_variant; missense_variant; NMD_transcript_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant. Polyphen Annotation: benign(ENST00000372755); probably damaging(ENST00000211998, ENST00000436396, LRG_383t1) SIFT Annotation: tolerated(ENST00000372755, ENST00000211998, ENST00000436396, LRG_383t1)
Consequence to Transcript	3_prime_UTR_variant(ENST00000624354); intron_variant(ENST00000478896); missense_variant(ENST00000372755, ENST00000211998, ENST00000436396, LRG_383t1); NMD_transcript_variant(ENST00000624354); non_coding_transcript_exon_variant(ENST00000623461); non_coding_transcript_variant(ENST00000478896, ENST00000623461); upstream_gene_variant(ENST00000472585)
No. of Studies	1 (Positive: 0; Negative: 0; Trend: 1)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Georgi, B., 2014	A/G		7 in BPI, 7 in Well 7 in BPI, 7 in Well	Top 30 Amish-specific putative damaging exonic missense vari...... Top 30 Amish-specific putative damaging exonic missense variants by prevalence in affected individuals. More...	Trend

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
VCL	vinculin	10q22.1-q23	1(0/0/1)

SNPs in LD with rs71579374 (count: 0) View in gBrowse (chr10:74100982..74100982 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)