SNP Report

Basic Info
Name rs71579374 dbSNP Ensembl
Location chr10:74100982 - 74100982(1)
Variant Alleles A/G
Ancestral Allele A
Minor Allele G
Minor Allele Frequence 3.99361E-4
Functional Annotation 3_prime_UTR_variant; intron_variant; missense_variant; NMD_transcript_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant.
Polyphen Annotation: benign(ENST00000372755); probably damaging(ENST00000211998, ENST00000436396, LRG_383t1)
SIFT Annotation: tolerated(ENST00000372755, ENST00000211998, ENST00000436396, LRG_383t1)
Consequence to Transcript 3_prime_UTR_variant(ENST00000624354); intron_variant(ENST00000478896); missense_variant(ENST00000372755, ENST00000211998, ENST00000436396, LRG_383t1); NMD_transcript_variant(ENST00000624354); non_coding_transcript_exon_variant(ENST00000623461); non_coding_transcript_variant(ENST00000478896, ENST00000623461); upstream_gene_variant(ENST00000472585)
No. of Studies 1 (Positive: 0; Negative: 0; Trend: 1)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Georgi, B., 2014 A/G 7 in BPI, 7 in Well 7 in BPI, 7 in Well Top 30 Amish-specific putative damaging exonic missense vari...... Top 30 Amish-specific putative damaging exonic missense variants by prevalence in affected individuals. More... Trend

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
VCL vinculin 10q22.1-q23 1(0/0/1)

SNPs in LD with rs71579374 (count: 0) View in gBrowse (chr10:74100982..74100982 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)