SNP Report

Basic Info

Name	rs45551636 dbSNP Ensembl
Location	chr16:23622972 - 23622972(1)
Variant Alleles	C/T
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.00858626
Functional Annotation	downstream_gene_variant; intron_variant; missense_variant; non_coding_transcript_variant; upstream_gene_variant. Polyphen Annotation: probably damaging(ENST00000261584, ENST00000568219, LRG_308t1) SIFT Annotation: deleterious(ENST00000261584, ENST00000568219, LRG_308t1)
Consequence to Transcript	downstream_gene_variant(ENST00000565038); intron_variant(ENST00000561764); missense_variant(ENST00000261584, ENST00000568219, LRG_308t1); non_coding_transcript_variant(ENST00000561764); upstream_gene_variant(ENST00000566069)
No. of Studies	1 (Positive: 0; Negative: 0; Trend: 1)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Georgi, B., 2014	C/T		GERP=5.84 GERP=5.84	Putative damaging exonic variants found in the five linkage ...... Putative damaging exonic variants found in the five linkage regions. More...	Trend

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
PALB2	partner and localizer of BRCA2	16p12.1	5(2/2/1)

SNPs in LD with rs45551636 (count: 0) View in gBrowse (chr16:23622972..23622972 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)