BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Region Report

Basic Info

Region Name	16p13
Chromosome Position	chr16:10400000-16700000
No. of Studies (Positive/Negative/Trend)	4(1/0/3)

Region related studies (count: 4)

Reference	Markers	Statistical Values	Author Comments	Result Category
Cassidy, F.,2007	TTTA028	Multipoint Linkage Analysis: narrow model, NPL = 1.99199, P-...... Multipoint Linkage Analysis: narrow model, NPL = 1.99199, P-value = 0.024227; Pairwise Linkage Analysis: Broad model, NPL = 1.49168, P-value = 0.068545; narrow model, NPL = 2.23042, P-value = 0.013655; Structure-Guided Linkage Analysis: Broad model: NPL = 1.77, P-value = 0.04 for all families.; NPL = 1.77, P-value = 0.039 for families.; Narrow model: NPL = 2.23, P-value = 0.014 for all families.; NPL = 2.75, P_value = 0.003 for 60% homogeneous families. More...	There is a trend for Significant linkage. There is a trend for Significant linkage.	Trend
McInnis, M. G.,2003(a)	D16S748	Linkage analysis: model E, Conditional NPL = 3.1, P-value = ...... Linkage analysis: model E, Conditional NPL = 3.1, P-value = 0.002 More...	Suggestive linkage was found in this region. Suggestive linkage was found in this region.	Trend
Jones, I.,2007	D16S423	linkage analysis: Max LOD score = 4.07 linkage analysis: Max LOD score = 4.07	Significant linkage was found in this region. Significant linkage was found in this region.	Positive
Georgi, B., 2014	D16S3127	expLOD=3.15 expLOD=3.15	The analysis of subpedigrees yielded nominally significant l...... The analysis of subpedigrees yielded nominally significant linkage peaks on 16p13 (expLOD 3.15 at D16S3127) within subpedigree 310. More...	Trend

Region related genes (count: 6)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
CLEC16A	C-type lectin domain family 16, member A	16p13.13	1(0/0/1)
ERCC4	excision repair cross-complementation group 4	16p13.3	1(0/0/1)
SHISA9	shisa family member 9	16p13.12	1(0/1/0)
GSPT1	G1 to S phase transition 1	16p13.1	1(0/0/1)
MKL2	MKL/myocardin-like 2	16p13.12	1(0/0/1)
NDE1	nudE neurodevelopment protein 1	16p13.11	1(1/0/0)

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Region: chr16:10400000..16700000 View in gBrowse