Region Report

Basic Info

Region Name	Chr 10
Chromosome Position	chr10:0-133797422
No. of Studies (Positive/Negative/Trend)	3(0/2/1)

Region related studies (count: 3)

Reference	Markers	Statistical Values	Author Comments	Result Category
Murphy, V. E.,2000	D10S198	Linkage analysis: broad model, NPL = -0.943, P-value = 0.85;...... Linkage analysis: broad model, NPL = -0.943, P-value = 0.85; narrow model, NPL = -0.301, P-value = 0.68 More...	No significant linkage was found in this region. No significant linkage was found in this region.	Negative
Badner, J. A.,2002		Meta analysis: Location: 156, Single Analysis MSP = 0.1, Bes...... Meta analysis: Location: 156, Single Analysis MSP = 0.1, Best Analysis MSP = 0.1 More...	No significant linkage was found in this region. No significant linkage was found in this region.	Negative
Foroud, T.,2000	D10S1423	Genome-Wide Linkage Results: LOD = 1.5 on Model I, LOD = 2.5...... Genome-Wide Linkage Results: LOD = 1.5 on Model I, LOD = 2.5 on Model II, LOD = 1.3 on Model III More...	Suggestive linkage was found in this region. Suggestive linkage was found in this region.	Trend

Region related genes (count: 56)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
PCDH15	protocadherin-related 15	10q21.1	4(2/1/1)
DIP2C	DIP2 disco-interacting protein 2 homolog C (Drosophila)	10p15.3	1(0/1/0)
EGR2	early growth response 2	10q21.1	3(1/2/0)
NT5C2	5'-nucleotidase, cytosolic II	10q24.32	2(2/0/0)
GRID1	glutamate receptor, ionotropic, delta 1	10q22	1(0/0/1)
ZMIZ1	zinc finger, MIZ-type containing 1	10q22.3	1(0/1/0)
CACNB2	calcium channel, voltage-dependent, beta 2 subunit	10p12	3(2/1/0)
TACC2	transforming, acidic coiled-coil containing protein 2	10q26	1(1/0/0)
CTNNA3	catenin (cadherin-associated protein), alpha 3	10q21	1(1/0/0)
GAD2	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	10p13-p11.2	1(0/1/0)
AS3MT	arsenite methyltransferase	10q24.33	1(1/0/0)
SNCG	synuclein, gamma (breast cancer-specific protein 1)	10q23.2-q23.3	1(0/1/0)
ADAM12	ADAM metallopeptidase domain 12	10q26	1(1/0/0)
PPP2R2D	protein phosphatase 2, regulatory subunit B, delta	10q26.3	1(0/0/1)
LGI1	leucine-rich, glioma inactivated 1	10q24	1(0/1/0)
PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	10p12.2	4(1/3/0)
OPTN	optineurin	10p14	1(0/0/1)
CFAP46	cilia and flagella associated protein 46	10q26.3	1(0/0/1)
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	10q25.3	1(1/0/0)
CTBP2	C-terminal binding protein 2	10q26.13	1(1/0/0)
TLL2	tolloid-like 2	10q23-q24	1(1/0/0)
IL15RA	interleukin 15 receptor, alpha	10p15.1	1(1/0/0)
CHAT	choline O-acetyltransferase	10q11.2	1(0/1/0)
VCL	vinculin	10q22.1-q23	1(0/0/1)
SVIL	supervillin	10p11.2	1(0/1/0)
CXCL12	chemokine (C-X-C motif) ligand 12	10q11.1	1(0/0/1)
FAM107B	family with sequence similarity 107, member B	10p14	1(1/0/0)
PNLIPRP1	pancreatic lipase-related protein 1	10q26.12	1(1/0/0)
PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme	10q22.2	2(1/1/0)
TCERG1L	transcription elongation regulator 1-like	10q26.3	1(0/0/1)
FGFR2	fibroblast growth factor receptor 2	10q25.3-q26	2(1/1/0)
CREM	cAMP responsive element modulator	10p12.1-p11.1	1(0/1/0)
ANKRD16	ankyrin repeat domain 16	10p15.1	1(1/0/0)
SLC18A2	solute carrier family 18 (vesicular monoamine transporter), member 2	10q25	1(1/0/0)
ADRA2A	adrenoceptor alpha 2A	10q25.2	1(0/1/0)
ZRANB1	zinc finger, RAN-binding domain containing 1	10q26.12	1(1/0/0)
KIAA1462	KIAA1462	10p12.1	1(0/1/0)
SLK	STE20-like kinase	10q25.1	1(0/0/1)
ZWINT	ZW10 interacting kinetochore protein	10q21-q22	1(1/0/0)
KAT6B	K(lysine) acetyltransferase 6B	10q22.2	1(1/0/0)
TFAM	transcription factor A, mitochondrial	10q21	1(1/0/0)
ANK3	ankyrin 3, node of Ranvier (ankyrin G)	10q21	17(13/3/1)
NRG3	neuregulin 3	10q23.1	2(0/2/0)
ATRNL1	attractin-like 1	10q26	1(0/1/0)
C10orf82	chromosome 10 open reading frame 82	10q26.12	1(1/0/0)
SIRT1	sirtuin 1	10q21	1(0/1/0)
GFRA1	GDNF family receptor alpha 1	10q25-q26	2(1/1/0)
PTPRE	protein tyrosine phosphatase, receptor type, E	10q26	1(1/0/0)
BTBD16	BTB (POZ) domain containing 16	10q26.13	2(1/0/1)
MYOZ1	myozenin 1	10q22.1	1(0/1/0)
INA	internexin neuronal intermediate filament protein, alpha	10q24	1(0/1/0)
HTR7	5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled	10q21-q24	2(0/2/0)
PRPF18	pre-mRNA processing factor 18	10p12.33	1(0/1/0)
C10orf120	chromosome 10 open reading frame 120	10q26.13	1(1/0/0)
KIF5B	kinesin family member 5B	10p11.22	1(0/0/1)
FBXO18	F-box protein, helicase, 18	10p15.1	1(1/0/0)

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Region: chr10:0..133797422 View in gBrowse