Gene Report

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Basic Info

Approved Symbol	KIAA1462
Symbol Alias	JCAD
Approved Name	KIAA1462
Name Alias	junctional protein associated with coronary artery disease
Location	10p12.1
Position	chr10:30012800-30115494, -1
External Links	HGNC: 29283 Entrez Gene: 57608 Ensembl: ENSG00000165757 UCSC: uc001iux.3
No. of Studies	1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Xu, W., 2014	SNP: rs12245803	The SNP within or near this gene did not achieve genome-wide significance.	Negative	Comment on Study

Gene functional annotation

Gene related GO terms (count: 3)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0007155	cell adhesion	biological process	IEA	42

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0005912	adherens junction	cellular component	IEA	4
GO:0005911	cell-cell junction	cellular component	IEA	16

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 1)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs12245803	chr10:30112521 - 30112521(1)	intron_variant; non_coding_transcript_variant	1(0/1/0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
10p11-p14	chr10:6600000-39800000	1 (0/1/0)
Chr 10	chr10:0-133797422	3 (0/2/1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

View in gBrowse

Region: chr10:30012800..30115494 View in gBrowse