Gene Report

Basic Info
Approved Symbol TFAM
Previous Symbol TCF6, TCF6L2
Approved Name transcription factor A, mitochondrial
Location 10q21
Position chr10:58385022-58399221, 1
External Links HGNC: 11741
Entrez Gene: 7019
Ensembl: ENSG00000108064
UCSC: uc001jkf.4
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Ament, S. A., 2015 P-value=0.0011, OR=14.9. No individual gene had a significant burden of segregating rare variants in BD pedigrees after correcting for multiple tests, although several genes had suggestive trends. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 25)

GO terms by PBA (count: 3)

GO terms by database search (count: 22)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 3)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 6)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr10:58385022..58399221 View in gBrowse
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