Gene Report

Basic Info
Approved Symbol GRID1
Symbol Alias GluD1, KIAA1220
Approved Name glutamate receptor, ionotropic, delta 1
Location 10q22
Position chr10:85599555-86366493, -1
External Links HGNC: 4575
Entrez Gene: 2894
Ensembl: ENSG00000182771
UCSC: uc001kdl.1
No. of Studies 1 (Positive: 0; Negative: 0; trend: 1)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Fallin, M. D.,2005 29 SNP typed, Median D'=0.21, Median r<sup>2</sup> =0.01, 13 LD blocks, 0.31 block coverage, there exists SNP or haplotype nominal P-value < 0.01 in SZ and P-value > 0.01 and <0.05 in BP and SZ/SZA.. This gene is highly suggestive to SZ and suggestive to BP. Trend Comment on Study
Gene functional annotation
Gene related GO terms (count: 11)

GO terms by PBA (count: 3)

GO terms by database search (count: 8)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 1)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 3)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 3)

Gene relationship with MDD

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Region: chr10:85599555..86366493 View in gBrowse
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