Gene Report

Basic Info
Approved Symbol INA
Previous Symbol NEF5
Symbol Alias NF-66
Approved Name internexin neuronal intermediate filament protein, alpha
Location 10q24
Position chr10:103277163-103290351, 1
External Links HGNC: 6057
Entrez Gene: 9118
Ensembl: ENSG00000148798
UCSC: uc001kws.3
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Fallin, M. D.,2005 3 SNP typed, Median D'=0.97, Median r<sup>2</sup> =0.88, 1 LD blocks, 0.81 block coverage, there exists SNP or haplotype nominal P-value < 0.01 in SZ and all SNP or haplotype P-value > 0.05 in BP.. This gene is not suggestive to BP. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 10)

GO terms by PBA (count: 1)

GO terms by database search (count: 9)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 1)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 4)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

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Region: chr10:103277163..103290351 View in gBrowse
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