BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Gene Report

Basic information

Related studies

Functional annotation

Related other genetic factors

Overlap with SZ and MDD

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Basic Info

Approved Symbol	BTBD16
Previous Symbol	C10orf87
Symbol Alias	FLJ25359, Em:AC061711.1
Approved Name	BTB (POZ) domain containing 16
Previous Name	chromosome 10 open reading frame 87
Location	10q26.13
Position	chr10:122271306-122338162, 1
External Links	HGNC: 26340 Entrez Gene: 118663 Ensembl: ENSG00000138152 UCSC: uc001lgc.1
No. of Studies	2 (Positive: 1; Negative: 0; trend: 1)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 2)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Smith, E. N.,2009	SNP: rs7078071	SNPs with the strongest statistical evidence for genetic background effects included rs11208285 in ROR1 at 1p31.3 (P=1.4E-06), rs4657247 in RGS5 at 1q23.3 (P=4.1E-06), and rs7078071 in BTBD16 at 10q26.13 (P=4.5E-06).	Trend	Comment on Study
Johnson, C.,2009		Monte-Carlo Simulation P-value = 0.0014. One of Genes That Harbor Overlapping Clusters of 4 Nominally Positive SNPs Whose Allele Frequencies Distinguish Individuals With Bipolar Disorder From Controls With P<0.05 Nominal Significance From at Least Three of the Four Samples in This Analysis	Positive	Comment on Study

Gene functional annotation

Gene related GO terms (count: 0)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 1)

Literature-origin SNPs (count: 1)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr10:122271306..122338162 View in gBrowse