Gene Report

Basic Info
Approved Symbol LGI1
Previous Symbol EPT
Symbol Alias IB1099, ETL1, EPITEMPIN
Approved Name leucine-rich, glioma inactivated 1
Previous Name epilepsy, partial
Location 10q24
Position chr10:93757809-93806272, 1
External Links HGNC: 6572
Entrez Gene: 9211
Ensembl: ENSG00000108231
UCSC: uc001kjc.4
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Fallin, M. D.,2005 5 SNP typed, Median D'=0.34, Median r<sup>2</sup> =0.04, 4 LD blocks, 0.02 block coverage, there exists SNP or haplotype nominal P-value > 0.01 and <0.05 in SZ/SZA and all SNP or haplotype P-value > 0.05 in BP.. This gene is suggestive to SZ/SZA , not suggestive to BP. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 13)

GO terms by PBA (count: 5)

GO terms by database search (count: 8)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 1)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 5)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

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Region: chr10:93757809..93806272 View in gBrowse
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