SNP Report

Basic Info

Name	rs252952 dbSNP Ensembl
Location	chr5:161287327 - 161287327(1)
Variant Alleles	T/G
Ancestral Allele	T
Minor Allele	G
Minor Allele Frequence	0.266374
Functional Annotation	downstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000274547, ENST00000393959)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Shi, J., 2008 (b)	A/C	C	Allelic association of neurotransmission systems genes with ...... Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0066, Gene-wide P-value = 0.1039 (P values were based on permutation for all SNPs in each gene). More...		Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
GABRB2	gamma-aminobutyric acid (GABA) A receptor, beta 2	5q34	1(1/0/0)

SNPs in LD with rs252952 (count: 6) View in gBrowse (chr5:161284971..161287789 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs252949	downstream_gene_variant	1.0[CEU]
rs252950	downstream_gene_variant	1.0[CEU]; 1.0[TSI]
rs153295	downstream_gene_variant	1.0[CEU]; 1.0[TSI]
rs252955	downstream_gene_variant	1.0[CEU]; 1.0[TSI]
rs252953	downstream_gene_variant	1.0[CEU]
rs252954	downstream_gene_variant	1.0[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)