SNP Report

Basic Info

Name	rs592403 dbSNP Ensembl
Location	chr5:161292977 - 161292977(1)
Variant Alleles	A/C
Ancestral Allele	C
Minor Allele	A
Minor Allele Frequence	0.484625
Functional Annotation	3_prime_UTR_variant; downstream_gene_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000274547, ENST00000393959); downstream_gene_variant(ENST00000353437, ENST00000517547, ENST00000517901, ENST00000520240)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Shi, J., 2008 (b)	A/C	C	Allelic association of neurotransmission systems genes with ...... Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0198, Gene-wide P-value = 0.2517 (P values were based on permutation for all SNPs in each gene). More...		Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
GABRB2	gamma-aminobutyric acid (GABA) A receptor, beta 2	5q34	1(1/0/0)

SNPs in LD with rs592403 (count: 3) View in gBrowse (chr5:161281834..161292977 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs252951	downstream_gene_variant	0.873[CEU]; 0.973[TSI]
rs252945		0.915[CEU]
rs252947	3_prime_UTR_variant; downstream_gene_variant	1.0[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)