SNP Report

Basic Info

Name	rs915841 dbSNP Ensembl
Location	chr21:42259328 - 42259328(1)
Variant Alleles	T/C
Ancestral Allele	T
Minor Allele	C
Minor Allele Frequence	0.209864
Functional Annotation	intron_variant; non_coding_transcript_variant; synonymous_variant.
Consequence to Transcript	intron_variant(ENST00000343687, ENST00000347800, ENST00000361802, ENST00000398449, ENST00000398457, ENST00000450121, ENST00000462050); non_coding_transcript_variant(ENST00000462050); synonymous_variant(ENST00000398437)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Shi, J., 2008 (b)	A/G	G	Allelic association of neurotransmission systems genes with ...... Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0494, Gene-wide P-value = 0.5205 (P values were based on permutation for all SNPs in each gene). More...		Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1	21q22.3	1(0/1/0)

SNPs in LD with rs915841 (count: 7) View in gBrowse (chr21:42253367..42261846 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs4148120	intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.923[CEU]
rs915843	intron_variant; missense_variant; non_coding_transcript_variant	1.0[CEU]; 1.0[TSI]
rs3787986	intron_variant; non_coding_transcript_variant	1.0[CEU]; 1.0[TSI]
rs7281684	intron_variant; missense_variant; non_coding_transcript_variant	1.0[CEU]
rs7281345	intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.923[CEU]; 0.908[TSI]
rs17114590	intron_variant; non_coding_transcript_variant	1.0[CEU]
rs915842	intron_variant; non_coding_transcript_variant; synonymous_variant	0.927[CEU]; 0.955[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)