SNP Report

Basic Info

Name	rs1461225 dbSNP Ensembl
Location	chr5:153803165 - 153803165(1)
Variant Alleles	T/G
Ancestral Allele	T
Minor Allele	T
Minor Allele Frequence	0.488818
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000285900, ENST00000340592, ENST00000448073, ENST00000518142, ENST00000518783, ENST00000521843)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Shi, J., 2008 (b)	A/C	C	Allelic association of neurotransmission systems genes with ...... Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0056, Gene-wide P-value = 0.0769 (P values were based on permutation for all SNPs in each gene). More...		Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
GRIA1	glutamate receptor, ionotropic, AMPA 1	5q33	2(2/0/0)

SNPs in LD with rs1461225 (count: 8) View in gBrowse (chr5:153803165..153837173 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs2926832	downstream_gene_variant	0.82[CEU]
rs1037892	intron_variant	1.0[CEU]; 1.0[TSI]
rs2964003		0.82[CEU]
rs2926862		0.82[CEU]
rs2926833	downstream_gene_variant	0.82[CEU]
rs2926865		0.812[CEU]
rs2926863		0.82[CEU]
rs1870739		0.82[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)