BDgene

SNP Report

Basic Info
Name rs1799281 dbSNP Ensembl
Location chr19:48445513 - 48445513(1)
Variant Alleles G/A
Ancestral Allele G
Minor Allele G
Minor Allele Frequence 0.448682
Functional Annotation downstream_gene_variant; upstream_gene_variant.
Consequence to Transcript downstream_gene_variant(ENST00000263269); upstream_gene_variant(ENST00000253237, ENST00000598711, ENST00000599949)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Shi, J., 2008 (b) A/G G Allelic association of neurotransmission systems genes with ...... Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0029, Gene-wide P-value = 0.026 (P values were based on permutation for all SNPs in each gene). More... rs1799281 in the GRIN2D gene reached gene-wide association. ...... rs1799281 in the GRIN2D gene reached gene-wide association. None of these associations survived multiple testing for its own system (e.g., glutamatergic or serotoninergic) or all the five systems taken together. More... Positive

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
GRWD1 glutamate-rich WD repeat containing 1 19q13.33 Mapped by Literature SNP
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 19q13.33 1(1/0/0)

SNPs in LD with rs1799281 (count: 1) View in gBrowse (chr19:48445039..48445513 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 1)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)