SNP Report

Basic Info

Name	rs362853 dbSNP Ensembl
Location	chr6:146391962 - 146391962(1)
Variant Alleles	C/A
Ancestral Allele	C
Minor Allele	A
Minor Allele Frequence	0.408546
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000282753, ENST00000355289, ENST00000361719, ENST00000492807, ENST00000507907)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Shi, J., 2008 (b)	A/C	A	Allelic association of neurotransmission systems genes with ...... Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0443, Gene-wide P-value = 0.3766 (P values were based on permutation for all SNPs in each gene). More...		Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
GRM1	glutamate receptor, metabotropic 1	6q24	Mapped by Literature SNP

SNPs in LD with rs362853 (count: 6) View in gBrowse (chr6:146369124..146395332 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs2328741	intron_variant	1.0[CEU]
rs362852	intron_variant	1.0[CEU]; 1.0[TSI]
rs362851	intron_variant	0.814[TSI]
rs362854	intron_variant	0.959[CEU]
rs9485078	intron_variant; upstream_gene_variant	0.957[CEU]; 0.93[TSI]
rs2328743	intron_variant	1.0[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)