SNP Report

Basic Info
Name rs733457 dbSNP Ensembl
Location chr6:34100631 - 34100631(1)
Variant Alleles G/A/T
Ancestral Allele T
Minor Allele G
Minor Allele Frequence 0.40016
Functional Annotation intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript intron_variant(ENST00000374177, ENST00000374181, ENST00000455714, ENST00000535756, ENST00000538487, ENST00000544773, ENST00000607916, ENST00000609222, ENST00000609278, ENST00000609973); NMD_transcript_variant(ENST00000609278); non_coding_transcript_variant(ENST00000607916, ENST00000609973); upstream_gene_variant(ENST00000609443)
No. of Studies 2 (Positive: 1; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 2)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Shi, J., 2008 (b) A/C C Allelic association of neurotransmission systems genes with ...... Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0249, Gene-wide P-value = 0.1399 (P values were based on permutation for all SNPs in each gene). More... Positive
Yosifova, A.,2009 G/T Allelic association: P-value = 0.61 Allelic association: P-value = 0.61 No significant association was observed No significant association was observed Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
GRM4 glutamate receptor, metabotropic 4 6p21.3 2(2/0/0)

SNPs in LD with rs733457 (count: 4) View in gBrowse (chr6:34100015..34101285 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 4)

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)