SNP Report

Basic Info

Name	rs623580 dbSNP Ensembl
Location	chr11:18042430 - 18042430(1)
Variant Alleles	A/T
Ancestral Allele	T
Minor Allele	A
Minor Allele Frequence	0.39357
Functional Annotation	upstream_gene_variant.
Consequence to Transcript	upstream_gene_variant(ENST00000250018, ENST00000417164, ENST00000528338)
No. of Studies	2 (Positive: 1; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Lai, T. J.,2005	T/A		chi-squared test: genotype, X²=2.17, P-value = 0....... chi-squared test: genotype, X²=2.17, P-value = 0.304; allele, X²=0.015, P-value = 0.946 More...	No significant association was observed. No significant association was observed.	Negative
Shi, J., 2008 (b)	A/T	T	Allelic association of neurotransmission systems genes with ...... Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0413, Gene-wide P-value = 0.0809 (P values were based on permutation for all SNPs in each gene). More...		Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
TPH1	tryptophan hydroxylase 1	11p15.3-p14	14(5/9/0)

SNPs in LD with rs623580 (count: 0) View in gBrowse (chr11:18042430..18042430 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)