SNP Report

Basic Info

Name	rs10743152 dbSNP Ensembl
Location	chr11:2174751 - 2174751(1)
Variant Alleles	T/C
Ancestral Allele	T
Minor Allele	T
Minor Allele Frequence	0.279952
Functional Annotation	downstream_gene_variant; upstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000584128); upstream_gene_variant(ENST00000324155, ENST00000333684, ENST00000352909, ENST00000381168, ENST00000381175, ENST00000381178)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Shi, J., 2008 (b)	A/G	A	Allelic association of neurotransmission systems genes with ...... Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.049, Gene-wide P-value = 0.2058 (P values were based on permutation for all SNPs in each gene). More...		Positive

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
TH	tyrosine hydroxylase	11p15.5	16(4/12/0)
MIR4686	microRNA 4686	11	Mapped by Literature SNP

SNPs in LD with rs10743152 (count: 4) View in gBrowse (chr11:2172367..2174751 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs10770140	upstream_gene_variant	1.0[CEU]
rs10770141	upstream_gene_variant	1.0[CEU]; 0.929[TSI]
rs7119275	downstream_gene_variant; upstream_gene_variant	1.0[CEU]
rs10840495	downstream_gene_variant; upstream_gene_variant	0.875[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)