SNP Report

Basic Info

Name	rs12754 dbSNP Ensembl
Location	chr7:45721595 - 45721595(1)
Variant Alleles	T/G
Ancestral Allele	G
Minor Allele	G
Minor Allele Frequence	0.19349
Functional Annotation	3_prime_UTR_variant; downstream_gene_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000297323); downstream_gene_variant(ENST00000338231, ENST00000413357, ENST00000428414, ENST00000429741, ENST00000444755)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Shi, J., 2008 (b)	A/C	C	Allelic association of neurotransmission systems genes with ...... Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.007, Gene-wide P-value = 0.1099 (P values were based on permutation for all SNPs in each gene). More...		Positive

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
ADCY1	adenylate cyclase 1 (brain)	7p12.3	Mapped by Literature SNP
SEPT7P2	septin 7 pseudogene 2	7p12.3	Mapped by Literature SNP

SNPs in LD with rs12754 (count: 7) View in gBrowse (chr7:45698202..45761447 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs11982719	intron_variant	0.899[CEU]; 0.968[TSI]
rs2280497	intron_variant	1.0[CEU]; 1.0[TSI]
rs1004028	intron_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CEU]; 1.0[TSI]
rs9993	downstream_gene_variant; intron_variant; non_coding_transcript_variant	1.0[CEU]; 1.0[TSI]
rs3735666	3_prime_UTR_variant; downstream_gene_variant	1.0[CEU]; 1.0[TSI]
rs17172610	downstream_gene_variant; intron_variant; non_coding_transcript_variant	1.0[CEU]; 1.0[TSI]
rs17172602	intron_variant	1.0[CEU]; 0.968[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)