BDgene

SNP Report

Basic Info
Name rs1048101 dbSNP Ensembl
Location chr8:26770511 - 26770511(1)
Variant Alleles A/G
Ancestral Allele G
Minor Allele A
Minor Allele Frequence 0.351837
Functional Annotation intron_variant; missense_variant; NMD_transcript_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant.
Polyphen Annotation: benign(ENST00000276393, ENST00000354550, ENST00000380573, ENST00000380582, ENST00000380586, ENST00000519229)
SIFT Annotation: tolerated(ENST00000276393, ENST00000354550, ENST00000380573, ENST00000380582, ENST00000380586, ENST00000519229)
Consequence to Transcript intron_variant(ENST00000519096, ENST00000521711); missense_variant(ENST00000276393, ENST00000354550, ENST00000380573, ENST00000380582, ENST00000380586, ENST00000519229); NMD_transcript_variant(ENST00000519096, ENST00000521711); non_coding_transcript_exon_variant(ENST00000518621); non_coding_transcript_variant(ENST00000518621); upstream_gene_variant(ENST00000486251)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Shi, J., 2008 (b) A/G G Allelic association of neurotransmission systems genes with ...... Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0306, Gene-wide P-value = 0.1888 (P values were based on permutation for all SNPs in each gene). More... Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
ADRA1A adrenoceptor alpha 1A 8p21.2 2(0/2/0)

SNPs in LD with rs1048101 (count: 10) View in gBrowse (chr8:26755891..26812200 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 10)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)