SNP Report

Basic Info
Name rs10515827 dbSNP Ensembl
Location chr5:161327950 - 161327950(1)
Variant Alleles C/T
Ancestral Allele C
Minor Allele T
Minor Allele Frequence 0.0557109
Functional Annotation downstream_gene_variant; intron_variant.
Consequence to Transcript downstream_gene_variant(ENST00000612710); intron_variant(ENST00000274547, ENST00000353437, ENST00000393959, ENST00000517547, ENST00000517901, ENST00000520240)
No. of Studies 2 (Positive: 2; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 2)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Perlis, 2008 Mean X2=8.1, P-value = 0.01 in gene-based associa...... Mean X2=8.1, P-value = 0.01 in gene-based association tests More... Positive
Shi, J., 2008 (b) A/G A Allelic association of neurotransmission systems genes with ...... Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0206, Gene-wide P-value = 0.1409 (P values were based on permutation for all SNPs in each gene). More... Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 5q34 1(1/0/0)

SNPs in LD with rs10515827 (count: 1) View in gBrowse (chr5:161327950..161414197 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 1)

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)