Region Report

Basic Info

Region Name	Chr 22
Chromosome Position	chr22:0-50818468
No. of Studies (Positive/Negative/Trend)	2(0/1/1)

Region related studies (count: 2)

Reference	Markers	Statistical Values	Author Comments	Result Category
Badner, J. A.,2002		Meta analysis: Location: 36, Single Analysis MSP = 0.00003, ...... Meta analysis: Location: 36, Single Analysis MSP = 0.00003, Replication MSP = 0.006; Best Analysis MSP = 0.00001, Replication MSP = 0.003 More...	Suggestive linkage was found in this region. Suggestive linkage was found in this region.	Trend
Murphy, V. E.,2000	D22S275	Linkage analysis: broad model, NPL = 0.292, P-value = 0.37; ...... Linkage analysis: broad model, NPL = 0.292, P-value = 0.37; narrow model, NPL = 0.214, P-value = 0.37 More...	No significant linkage was found in this region. No significant linkage was found in this region.	Negative

Region related genes (count: 59)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
PICK1	protein interacting with PRKCA 1	22q13.1	1(0/1/0)
COMT	catechol-O-methyltransferase	22q11.21	28(14/14/0)
ZDHHC8	zinc finger, DHHC-type containing 8	22q11.21	1(0/1/0)
MLC1	megalencephalic leukoencephalopathy with subcortical cysts 1	22q13.33	5(1/4/0)
SYNGR1	synaptogyrin 1	22q13	3(2/1/0)
CYTH4	cytohesin 4	22q12.3-q13.1	1(1/0/0)
TFIP11	tuftelin interacting protein 11	22q12.1	1(1/0/0)
MED15	mediator complex subunit 15	22q11.2	1(0/1/0)
GNAZ	guanine nucleotide binding protein (G protein), alpha z polypeptide	22q11.1-q11.2	1(1/0/0)
TNRC6B	trinucleotide repeat containing 6B	22q13	1(1/0/0)
DGCR14	DiGeorge syndrome critical region gene 14	22q11.21	1(0/1/0)
CACNG2	calcium channel, voltage-dependent, gamma subunit 2	22q13.1	3(3/0/0)
BCR	breakpoint cluster region	22q11	2(1/1/0)
LARGE	like-glycosyltransferase	22q12.3	1(1/0/0)
DGCR6L	DiGeorge syndrome critical region gene 6-like	22q11.21	1(0/1/0)
UFD1L	ubiquitin fusion degradation 1 like (yeast)	22q11.2	1(0/1/0)
SNAP29	synaptosomal-associated protein, 29kDa	22q11.21	3(1/2/0)
IL17RA	interleukin 17 receptor A	22q11.1	1(0/1/0)
PLA2G6	phospholipase A2, group VI (cytosolic, calcium-independent)	22q13.1	2(1/1/0)
RTN4R	reticulon 4 receptor	22q11	1(0/1/0)
CABIN1	calcineurin binding protein 1	22q11.23	1(0/0/1)
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta	22q12.1-q13.1	3(2/0/1)
PRODH	proline dehydrogenase (oxidase) 1	22q11.2	4(0/4/0)
TOM1	target of myb1 (chicken)	22q13.1	1(1/0/0)
IL2RB	interleukin 2 receptor, beta	22q13	2(1/1/0)
MYO18B	myosin XVIIIB	22q12.1	2(0/2/0)
MOV10L1	Mov10 RISC complex RNA helicase like 1	22q13.33	1(0/1/0)
CRYBB2P1	crystallin, beta B2 pseudogene 1	22q11.2-q12.1	1(0/0/1)
ZNF74	zinc finger protein 74	22q11.2	1(0/1/0)
GNB1L	guanine nucleotide binding protein (G protein), beta polypeptide 1-like	22q11.2	1(1/0/0)
FAM83F	family with sequence similarity 83, member F	22q13.1	1(0/1/0)
HMGXB4	HMG box domain containing 4	22q13	1(1/0/0)
MTMR3	myotubularin related protein 3	22q12.2	1(0/1/0)
OSBP2	oxysterol binding protein 2	22q12.2	1(0/1/0)
UBE2L3	ubiquitin-conjugating enzyme E2L 3	22q11.2	1(0/1/0)
DGCR6	DiGeorge syndrome critical region gene 6	22q11.21	1(0/1/0)
CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	22q12.3	2(1/1/0)
PARVB	parvin, beta	22q13.2-q13.33	1(1/0/0)
GSC2	goosecoid homeobox 2	22q11.21	1(0/1/0)
CSNK1E	casein kinase 1, epsilon	22q13.1	5(1/3/1)
PI4KA	phosphatidylinositol 4-kinase, catalytic, alpha	22q11.21	3(1/2/0)
SEZ6L	seizure related 6 homolog (mouse)-like	22q12.1	1(1/0/0)
TSPO	translocator protein (18kDa)	22q13.3	3(1/2/0)
XBP1	X-box binding protein 1	22q12.1	3(2/1/0)
GSTT1	glutathione S-transferase theta 1	22q11.23 alternate reference locus	1(1/0/0)
ADSL	adenylosuccinate lyase	22q13.1	2(1/1/0)
ST13	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	22q13.2	1(1/0/0)
TPST2	tyrosylprotein sulfotransferase 2	22q12.1	2(1/0/1)
DGCR8	DGCR8 microprocessor complex subunit	22q11.2	2(1/0/1)
PARVG	parvin, gamma	22q13.31	1(1/0/0)
TUBA8	tubulin, alpha 8	22q11	2(1/1/0)
ATF4	activating transcription factor 4	22q13.1	1(1/0/0)
HPS4	Hermansky-Pudlak syndrome 4	22q12.1	1(1/0/0)
BRD1	bromodomain containing 1	22q13.33	2(2/0/0)
PRR5	proline rich 5 (renal)	22q13.3	1(0/0/1)
MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2	22q13.33	1(0/1/0)
ZBED4	zinc finger, BED-type containing 4	22q13.33	1(1/0/0)
MCHR1	melanin-concentrating hormone receptor 1	22q13.3	2(1/1/0)
ADRBK2	adrenergic, beta, receptor kinase 2	22q11	3(2/1/0)

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Region: chr22:0..50818468 View in gBrowse