BDgene

Gene Report

Basic Info
Approved Symbol UBE2L3
Symbol Alias UBCH7
Approved Name ubiquitin-conjugating enzyme E2L 3
Location 22q11.2
Position chr22:21549447-21624034, 1
External Links HGNC: 12488
Entrez Gene: 7332
Ensembl: ENSG00000185651
UCSC: uc031rxe.1
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Fallin, M. D.,2005 2 SNP typed, Median D'=1, Median r<sup>2</sup> =1, 1 LD blocks, 0.3 block coverage, all SNP or haplotype P-value > 0.05 in BP and SZ/SZA... This gene is not suggestive to BP. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 28)

GO terms by PBA (count: 1)

GO terms by database search (count: 27)


Gene related KEGG pathways (count: 2)

KEGG pathways by PBA (count: 1)

KEGG pathways by database search (count: 1)


Gene related BioCarta pathways (count: 1)

BioCarta pathways by PBA (count: 0)

BioCarta pathways by database search (count: 1)


Gene related interactors from protein-protein interactions data in HPRD (count: 17)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 1)


Gene relationship with MDD

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Region: chr22:21549447..21624034 View in gBrowse
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