Gene Report

Basic Info
Approved Symbol PICK1
Previous Symbol PRKCABP
Symbol Alias dJ1039K5, MGC15204
Approved Name protein interacting with PRKCA 1
Previous Name protein kinase C, alpha binding protein, "protein interacting with PRKCA"
Location 22q13.1
Position chr22:38056311-38075701, 1
External Links HGNC: 9394
Entrez Gene: 9463
Ensembl: ENSG00000100151
UCSC: uc003aus.3
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Fallin, M. D.,2005 5 SNP typed, Median D'=1, Median r<sup>2</sup> =0.28, 1 LD blocks, 0.84 block coverage, all SNP or haplotype P-value > 0.05 in BP and SZ/SZA. This gene is not suggestive to BP. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 45)

GO terms by PBA (count: 7)

GO terms by database search (count: 38)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 33)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 5)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 5)

Gene relationship with MDD

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Region: chr22:38056311..38075701 View in gBrowse
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