Gene Report

Basic Info
Approved Symbol DGCR14
Previous Symbol DGCR13
Symbol Alias DGSI, Es2el, ES2, DGS-H
Approved Name DiGeorge syndrome critical region gene 14
Previous Name DiGeorge syndrome critical region gene 13
Location 22q11.21
Position chr22:19130279-19144684, -1
External Links HGNC: 16817
Entrez Gene: 8220
Ensembl: ENSG00000100056
UCSC: uc002zou.3
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Fallin, M. D.,2005 5 SNP typed, Median D'=0.94, Median r<sup>2</sup> =0.17, 2 LD blocks, 0.65 block coverage, all SNP or haplotype P-value > 0.05 in BP and SZ/SZA.. This gene is not suggestive to BP. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 6)

GO terms by PBA (count: 3)

GO terms by database search (count: 3)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 1)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 4)

Gene relationship with MDD

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Region: chr22:19130279..19144684 View in gBrowse
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