Approved Symbol
|
Approved Name |
Location
|
No. of Studies (Positive/Negative/Trend) 
|
Overlap with SZ
|
Overlap with MDD
|
All
|
| SLC6A4 |
solute carrier family 6 (neurotransmitter transporter), member 4 |
17q11.2 |
44(18/26/0)
|
YES
|
YES
|
|
| BDNF |
brain-derived neurotrophic factor |
11p14.1 |
37(24/12/1)
|
YES
|
YES
|
|
| COMT |
catechol-O-methyltransferase |
22q11.21 |
28(14/14/0)
|
YES
|
YES
|
|
| DRD2 |
dopamine receptor D2 |
11q22-q23 |
28(8/20/0)
|
YES
|
YES
|
|
| HTR2A |
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled |
13q14-q21 |
22(7/15/0)
|
YES
|
YES
|
|
| DAOA |
D-amino acid oxidase activator |
13q33.2 |
21(13/7/1)
|
YES
|
YES
|
|
| MAOA |
monoamine oxidase A |
Xp11.4-p11.3 |
21(10/11/0)
|
YES
|
YES
|
|
| CACNA1C |
calcium channel, voltage-dependent, L type, alpha 1C subunit |
12p13.3 |
20(17/3/0)
|
YES
|
YES
|
|
| DRD3 |
dopamine receptor D3 |
3q13.3 |
19(4/15/0)
|
YES
|
YES
|
|
| DISC1 |
disrupted in schizophrenia 1 |
1q42.1 |
18(10/7/1)
|
YES
|
YES
|
|
| ANK3 |
ankyrin 3, node of Ranvier (ankyrin G) |
10q21 |
17(13/3/1)
|
YES
|
YES
|
|
| TH |
tyrosine hydroxylase |
11p15.5 |
16(4/12/0)
|
YES
|
YES
|
|
| MTHFR |
methylenetetrahydrofolate reductase (NAD(P)H) |
1p36.3 |
16(10/6/0)
|
YES
|
YES
|
|
| NRG1 |
neuregulin 1 |
8p12 |
15(10/5/0)
|
YES
|
YES
|
|
| TPH1 |
tryptophan hydroxylase 1 |
11p15.3-p14 |
14(5/9/0)
|
YES
|
YES
|
|
| TPH2 |
tryptophan hydroxylase 2 |
12q15 |
13(10/3/0)
|
YES
|
YES
|
|
| DRD4 |
dopamine receptor D4 |
11p15.5 |
13(1/12/0)
|
YES
|
YES
|
|
| CLOCK |
clock circadian regulator |
4q12 |
12(5/7/0)
|
YES
|
YES
|
|
| SLC6A3 |
solute carrier family 6 (neurotransmitter transporter), member 3 |
5p15.3 |
11(5/6/0)
|
YES
|
YES
|
|
| DRD1 |
dopamine receptor D1 |
5q34-q35 |
11(6/5/0)
|
YES
|
YES
|
|
| P2RX7 |
purinergic receptor P2X, ligand gated ion channel, 7 |
12q24 |
9(2/7/0)
|
YES
|
YES
|
|
| GSK3B |
glycogen synthase kinase 3 beta |
3q13.3 |
8(0/8/0)
|
YES
|
YES
|
|
| DTNBP1 |
dystrobrevin binding protein 1 |
6p22.3 |
8(4/3/1)
|
YES
|
YES
|
|
| NOS1 |
nitric oxide synthase 1 (neuronal) |
12q24.22 |
8(2/5/1)
|
YES
|
YES
|
|
| GRIN2B |
glutamate receptor, ionotropic, N-methyl D-aspartate 2B |
12p13.1 |
8(4/4/0)
|
YES
|
YES
|
|
| WFS1 |
Wolfram syndrome 1 (wolframin) |
4p16.1 |
7(1/6/0)
|
YES
|
YES
|
|
| PER2 |
period circadian clock 2 |
2q37.3 |
7(1/6/0)
|
YES
|
YES
|
|
| GRM3 |
glutamate receptor, metabotropic 3 |
7q21.1-q21.2 |
7(3/4/0)
|
YES
|
YES
|
|
| PER3 |
period circadian clock 3 |
1p36.23 |
7(3/4/0)
|
YES
|
YES
|
|
| ARNTL |
aryl hydrocarbon receptor nuclear translocator-like |
11p15 |
7(5/2/0)
|
YES
|
YES
|
|
| KCNN3 |
potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 |
1q21.3 |
7(1/6/0)
|
YES
|
YES
|
|
| HTR2C |
5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled |
Xq23 |
7(4/3/0)
|
YES
|
YES
|
|
| NDUFV2 |
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa |
18p11.22 |
6(5/1/0)
|
YES
|
NO
|
|
| ZNF804A |
zinc finger protein 804A |
2q32.1 |
6(3/3/0)
|
YES
|
NO
|
|
| SYNE1 |
spectrin repeat containing, nuclear envelope 1 |
6q25.2 |
6(3/2/1)
|
YES
|
YES
|
|
| NR1D1 |
nuclear receptor subfamily 1, group D, member 1 |
17q11.2 |
6(2/4/0)
|
YES
|
YES
|
|
| TENM4 |
teneurin transmembrane protein 4 |
11q13 |
6(4/2/0)
|
YES
|
YES
|
|
| RBFOX1 |
RNA binding protein, fox-1 homolog (C. elegans) 1 |
16p13.3 |
6(2/2/2)
|
NO
|
NO
|
|
| GABRA5 |
gamma-aminobutyric acid (GABA) A receptor, alpha 5 |
15q12 |
6(6/0/0)
|
YES
|
YES
|
|
| RGS4 |
regulator of G-protein signaling 4 |
1q23.3 |
6(3/2/1)
|
YES
|
YES
|
|
| DGKH |
diacylglycerol kinase, eta |
13q13.3 |
6(3/3/0)
|
YES
|
YES
|
|
| TCF4 |
transcription factor 4 |
18q21.1 |
6(1/5/0)
|
YES
|
NO
|
|
| MAD1L1 |
MAD1 mitotic arrest deficient-like 1 (yeast) |
7p22 |
5(1/2/2)
|
YES
|
NO
|
|
| MLC1 |
megalencephalic leukoencephalopathy with subcortical cysts 1 |
22q13.33 |
5(1/4/0)
|
YES
|
YES
|
|
| SORCS2 |
sortilin-related VPS10 domain containing receptor 2 |
4p16.1 |
5(3/2/0)
|
NO
|
NO
|
|
| PALB2 |
partner and localizer of BRCA2 |
16p12.1 |
5(2/2/1)
|
YES
|
NO
|
|
| TAAR6 |
trace amine associated receptor 6 |
6q23.1 |
5(4/1/0)
|
YES
|
YES
|
|
| NPAS2 |
neuronal PAS domain protein 2 |
2q11.2 |
5(3/2/0)
|
YES
|
YES
|
|
| PDLIM5 |
PDZ and LIM domain 5 |
4q22 |
5(4/1/0)
|
YES
|
YES
|
|
| CSNK1E |
casein kinase 1, epsilon |
22q13.1 |
5(1/3/1)
|
YES
|
YES
|
|
| CNR1 |
cannabinoid receptor 1 (brain) |
6q14-q15 |
5(0/5/0)
|
YES
|
YES
|
|
| PBRM1 |
polybromo 1 |
3p21 |
5(4/0/1)
|
YES
|
YES
|
|
| TRPM2 |
transient receptor potential cation channel, subfamily M, member 2 |
21q22.3 |
5(3/2/0)
|
NO
|
NO
|
|
| NR3C1 |
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
5q31-q32 |
5(2/3/0)
|
YES
|
YES
|
|
| DDC |
dopa decarboxylase (aromatic L-amino acid decarboxylase) |
7p12.1 |
5(2/3/0)
|
YES
|
YES
|
|
| FKBP5 |
FK506 binding protein 5 |
6p21.31 |
5(1/4/0)
|
YES
|
YES
|
|
| ACE |
angiotensin I converting enzyme |
17q23.3 |
5(2/3/0)
|
YES
|
YES
|
|
| DAO |
D-amino-acid oxidase |
12q24.11 |
5(1/4/0)
|
YES
|
NO
|
|
| CRY2 |
cryptochrome circadian clock 2 |
11p11.2 |
5(3/2/0)
|
YES
|
YES
|
|
| TRANK1 |
tetratricopeptide repeat and ankyrin repeat containing 1 |
3p22.2 |
5(2/1/2)
|
YES
|
NO
|
|
| PER1 |
period circadian clock 1 |
17p13.1 |
5(2/3/0)
|
YES
|
YES
|
|
| DUSP6 |
dual specificity phosphatase 6 |
12q22-q23 |
5(3/2/0)
|
YES
|
YES
|
|
