GO Report

Basic Info
ID GO:0042493
Name response to drug
Type biological process
No. of Genes in BDgene  57
Source Pathway by Database Search

PBA Result

GO related genes in BDgene (count: 57)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend) Evidence[PMID]
TSPO translocator protein (18kDa) 22q13.3 3(1/2/0) IEA
ANXA1 annexin A1 9q21.13 1(0/0/1) IEA
IL6 interleukin 6 7p21-p15 1(0/1/0) IEA
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 1p36-p35 3(1/2/0) IEA
DUSP6 dual specificity phosphatase 6 12q22-q23 5(3/2/0) IEA
SNCG synuclein, gamma (breast cancer-specific protein 1) 10q23.2-q23.3 1(0/1/0) IEA
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 16p13.2 1(1/0/0) IEA
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 2q31 2(1/1/0) IEA
MAP2K6 mitogen-activated protein kinase kinase 6 17q 1(0/1/0) IEA
IFNG interferon, gamma 12q14 2(2/0/0) IEA
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled Xq23 7(4/3/0) IDA[18703043]
SOD2 superoxide dismutase 2, mitochondrial 6q25 2(1/1/0) IEA
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 1p36.3 16(10/6/0) IEA
MAOB monoamine oxidase B Xp11.4-p11.3 4(2/2/0) IEA
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 15q12 1(0/1/0) IEA
CREB1 cAMP responsive element binding protein 1 2q34 2(1/1/0) IEA
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 12q24 9(2/7/0) IEA
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 6p12 1(0/1/0) IEA
GSK3B glycogen synthase kinase 3 beta 3q13.3 8(0/8/0) IEA
GCLM glutamate-cysteine ligase, modifier subunit 1p21 1(0/0/1) IDA[9895302]
XBP1 X-box binding protein 1 22q12.1 3(2/1/0) IEA
NNMT nicotinamide N-methyltransferase 11q23.1 1(1/0/0) IEA
FABP3 fatty acid binding protein 3, muscle and heart 1p33-p32 2(1/1/0) IEA
NGF nerve growth factor (beta polypeptide) 1p13.1 2(1/1/0) IEA
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 7q21.12 1(1/0/0) TAS[3022150]
CRH corticotropin releasing hormone 8q13 2(1/1/0) IEA
DRD2 dopamine receptor D2 11q22-q23 28(8/20/0) ISS
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 19q13.2 3(2/1/0) IEA
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) 2p23.1 1(0/1/0) IEA
DRD3 dopamine receptor D3 3q13.3 19(4/15/0) ISS
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 1p32.3 1(1/0/0) IEA
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 16q12.2 2(0/2/0) IEA
IL10 interleukin 10 1q31-q32 1(0/1/0) IEA
DPYSL2 dihydropyrimidinase-like 2 8p22-p21 2(1/0/1) IEA
FYN FYN proto-oncogene, Src family tyrosine kinase 6q21 1(1/0/0) IEA
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 13q14-q21 22(7/15/0) IDA[15862800]
APOD apolipoprotein D 3q29 1(0/1/0) ISS
ADRA1A adrenoceptor alpha 1A 8p21.2 2(0/2/0) ISS
COMT catechol-O-methyltransferase 22q11.21 28(14/14/0) IEA
DRD1 dopamine receptor D1 5q34-q35 11(6/5/0) ISS
SRR serine racemase 17p13 1(0/1/0) IEA
IL1RN interleukin 1 receptor antagonist 2q14.2 2(2/0/0) IEA
TNF tumor necrosis factor 6p21.3 4(2/2/0) IEA
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 10p13-p11.2 1(0/1/0) IEA
BCL2 B-cell CLL/lymphoma 2 18q21.3 2(0/2/0) IDA[36599]; IMP[17875758]
OXTR oxytocin receptor 3p25 1(0/1/0) IEA
BDH1 3-hydroxybutyrate dehydrogenase, type 1 3q29 2(1/1/0) IEA
SST somatostatin 3q28 1(0/1/0) IEA
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 1p32-p31 1(0/1/0) IEA
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1p13 1(1/0/0) IEA
OXCT1 3-oxoacid CoA transferase 1 5p13 1(1/0/0) IEA
CPB2 carboxypeptidase B2 (plasma) 13q14.11 1(1/0/0) IEA
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 17q11.2 44(18/26/0) IEA
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 11p13-p12 1(1/0/0) IEA
GNAS GNAS complex locus 20q13.2-q13.3 1(0/1/0) IEA
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 5p15.3 11(5/6/0) IEA
GNA12 guanine nucleotide binding protein (G protein) alpha 12 7p22.3 1(1/0/0) IEA