Gene Report

Basic Info
Approved Symbol CRH
Symbol Alias CRF, CRH1
Approved Name corticotropin releasing hormone
Name Alias corticotropin-releasing factor, "corticoliberin"
Location 8q13
Position chr8:66176382-66178725, -1
External Links HGNC: 2355
Entrez Gene: 1392
Ensembl: ENSG00000147571
UCSC: uc003xvy.2
No. of Studies 2 (Positive: 1; Negative: 1; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Gratacos, M.,2009 SNP: rs6999100 Nominal associations with bipolar disorder was observed. Positive Comment on Study
Alda, M.,2000 Other variant: CRH_polymorphisms In conclusion, our study does not support the hypothesis that genes coding for CRH or PENK contribute to the genetic susceptibility to bipolar disorder. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 64)

GO terms by PBA (count: 5)

GO terms by database search (count: 59)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 1)

KEGG pathways by database search (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 1)

Related other genetic factors
Gene related SNPs (count: 1)

Literature-origin SNPs (count: 1)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 1)

Gene related regions (count: 4)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr8:66176382..66178725 View in gBrowse
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