Gene Report

Basic Info
Approved Symbol MAP2K6
Previous Symbol PRKMK6
Symbol Alias MEK6, MKK6, SAPKK3, MAPKK6
Approved Name mitogen-activated protein kinase kinase 6
Name Alias protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6)
Location 17q
Position chr17:69414698-69543331, 1
External Links HGNC: 6846
Entrez Gene: 5608
Ensembl: ENSG00000108984
UCSC: uc002jij.3
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Xu, W., 2014 SNP: rs11869073 The SNP within or near this gene did not achieve genome-wide significance. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 44)

GO terms by PBA (count: 1)

GO terms by database search (count: 43)

Gene related KEGG pathways (count: 4)

KEGG pathways by PBA (count: 1)

KEGG pathways by database search (count: 3)

Gene related BioCarta pathways (count: 11)

Gene related interactors from protein-protein interactions data in HPRD (count: 13)

Related other genetic factors
Gene related SNPs (count: 2)

Literature-origin SNPs (count: 1)

LD-proxies (count: 1)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr17:69414698..69543331 View in gBrowse
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