BDgene

Study Report

Basic Info
Reference
Citation Moskvina, V., N. Craddock, et al. (2009). Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk. Mol Psychiatry 14(3): 252-260.
Disease Type Bipolar Disorder & Schizophrenia
Study Design case-control
Study Type Genome-wide association study
Sample Size 1868 bipolar disorder cases,479 UK schizophrenia cases and 2938 controls
SNP/Region/Marker Size 145,344 SNPs
Predominant Ethnicity
Population WTCCC collection and British

Detail Info

Genetic factors reported by this study for BD
Genes reported by this study for BD (count: 52)

Genetic factors reported by this study for SZ and/or MDD
Genes reported by this study for SZ/MDD
Disease Gene Description Result Category
SZ CAPN10 It showed no evidence for association with SZ. Negative
SZ LRRC36 It showed no evidence for association with SZ. Negative
SZ SEMG2 In SZ:Smallest P-value per gene=0.00387, Product of P truncation <=0.01=0.00387, Product of P truncation <=0.001=NA It showed evidence for association with SZ. Positive
SZ ANKRD35 It showed no evidence for association with SZ. Negative
SZ FLVCR2 It showed no evidence for association with SZ. Negative
SZ KLHDC1 It showed no evidence for association with SZ. Negative
SZ CPB2 It showed no evidence for association with SZ. Negative
SZ WDFY2 In SZ:Smallest P-value per gene=0.01216, Product of P truncation <=0.01=0.0046, Product of P truncation <=0.001=NA It showed evidence for association with SZ. Positive
SZ FABP3 It showed no evidence for association with SZ. Negative
SZ POLE2 It showed no evidence for association with SZ. Negative
SZ TMEM108 In SZ:Smallest P-value per gene=0.00038, Product of P truncation <=0.01=0.00006, Product of P truncation <=0.001=0.00007 It showed evidence for association with SZ. Positive
SZ PTPRE It showed no evidence for association with SZ. Negative
SZ CDKN2A In SZ:Smallest P-value per gene=0.00132, Product of P truncation <=0.01=0.00132, Product of P truncation <=0.001=NA It showed evidence for association with SZ. Positive
SZ DPP10 It showed no evidence for association with SZ. Negative
SZ PSKH1 In SZ:Smallest P-value per gene=0.00777, Product of P truncation <=0.01=0.00777, Product of P truncation <=0.001=NA It showed evidence for association with SZ. Positive
SZ PTGR2 It showed no evidence for association with SZ. Negative
SZ CSF2RB It showed no evidence for association with SZ. Negative
SZ ZNF490 It showed no evidence for association with SZ. Negative
SZ TCAF1 It showed no evidence for association with SZ. Negative
SZ TDRD9 It showed no evidence for association with SZ. Negative
SZ ZNF274 It showed no evidence for association with SZ. Negative
SZ THSD7A It showed no evidence for association with SZ. Negative
SZ ZNF284 It showed no evidence for association with SZ. Negative
SZ INTS6 In SZ:Smallest P-value per gene=0.00079, Product of P truncation <=0.01=0.00039, Product of P truncation <=0.001=0.00023 It showed evidence for association with SZ. Positive
SZ LRR1 It showed no evidence for association with SZ. Negative
SZ SVEP1 It showed no evidence for association with SZ. Negative
SZ CMTM8 It showed no evidence for association with SZ. Negative
SZ MYL12A In SZ:Smallest P-value per gene=0.00106, Product of P truncation <=0.01=0.00096, Product of P truncation <=0.001=0.00124 It showed evidence for association with SZ. Positive
SZ TLE4 It showed no evidence for association with SZ. Negative
SZ PBRM1 In SZ:Smallest P-value per gene=0.00107, Product of P truncation <=0.01=0.00082, Product of P truncation <=0.001=0.00063 It showed evidence for association with SZ. Positive
SZ FBXO38 In SZ:Smallest P-value per gene=0.00456, Product of P truncation <=0.01=0.0053, Product of P truncation <=0.001=NA It showed evidence for association with SZ. Positive
SZ JAM3 In SZ:Smallest P-value per gene=0.00396, Product of P truncation <=0.01=0.00213, Product of P truncation <=0.001=0.00112 It showed evidence for association with SZ. Positive
SZ PFN4 In SZ:Smallest P-value per gene=0.00045, Product of P truncation <=0.01=0.00045, Product of P truncation <=0.001=0.00045 It showed evidence for association with SZ. Positive
SZ HOXA3 It showed no evidence for association with SZ. Negative
SZ AKAP10 It showed no evidence for association with SZ. Negative
SZ ATP6V0D1 It showed no evidence for association with SZ. Negative
SZ C10orf120 In SZ:Smallest P-value per gene=0.00583, Product of P truncation <=0.01=0.00591, Product of P truncation <=0.001=NA It showed evidence for association with SZ. Positive
SZ GNL3 In SZ:Smallest P-value per gene=0.00812, Product of P truncation <=0.01=0.00819, Product of P truncation <=0.001=NA It showed evidence for association with SZ. Positive
SZ LAMP3 It showed no evidence for association with SZ. Negative
SZ MCM3AP-AS1 It showed no evidence for association with SZ. Negative
SZ GLT8D1 In SZ:Smallest P-value per gene=0.00608, Product of P truncation <=0.01=0.00608, Product of P truncation <=0.001=NA It showed evidence for association with SZ. Positive
SZ NCAPD3 In SZ:Smallest P-value per gene=0.00135, Product of P truncation <=0.01=0.00064, Product of P truncation <=0.001=0.00137 It showed evidence for association with SZ. Positive
SZ TP53I3 In SZ:Smallest P-value per gene=0.00028, Product of P truncation <=0.01=0.00028, Product of P truncation <=0.001=0.00028 It showed evidence for association with SZ. Positive
SZ SIGLEC6 It showed no evidence for association with SZ. Negative
SZ DFNB31 It showed no evidence for association with SZ. Negative
SZ ITIH3 In SZ:Smallest P-value per gene=0.0005, Product of P truncation <=0.01=0.0005, Product of P truncation <=0.001=0.0005 It showed evidence for association with SZ. Positive
SZ CACNA1C It showed no evidence for association with SZ. Negative
SZ RNPEPL1 It showed no evidence for association with SZ. Negative
SZ PALB2 It showed no evidence for association with SZ. Negative
SZ RSRC2 It showed no evidence for association with SZ. Negative
SZ MYL12B In SZ:Smallest P-value per gene=0.00022, Product of P truncation <=0.01=0.01111, Product of P truncation <=0.001=0.00129 It showed evidence for association with SZ. Positive
SZ NEK4 In SZ:Smallest P-value per gene=0.00199, Product of P truncation <=0.01=0.00196, Product of P truncation <=0.001=0.00199 It showed evidence for association with SZ. Positive