Gene Report

ADD to My Gene Set

Basic Info

Approved Symbol	WDFY2
Symbol Alias	ZFYVE22
Approved Name	WD repeat and FYVE domain containing 2
Previous Name	WD40 and FYVE domain containing 2
Location	13q14.12
Position	chr13:51584455-51767707, 1
External Links	HGNC: 20482 Entrez Gene: 115825 Ensembl: ENSG00000139668 UCSC: uc001vfp.3
No. of Studies	1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ?	YES
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Moskvina, V.,2009		In BD:Smallest P-value per gene=0.04086, Product of P truncation <=0.01=0.00399, Product of P truncation <=0.001=NA. It showed evidence for association with BD.	Positive	Comment on Study

Gene functional annotation

Gene related GO terms (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0046872	metal ion binding	molecular function	IEA	115

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
13q12-14	chr13:18900000-54700000	1 (0/1/0)
13q14	chr13:39500000-54700000	3 (0/1/2)
13q13-q14	chr13:31600000-54700000	1 (1/0/0)
Chr 13	chr13:0-114364328	1 (0/0/1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Reference	Description	Result Category
19065143	In SZ:Smallest P-value per gene=0.01216, Product of P truncation <=0.01=0.0046, Product of P truncation <=0.001=NA It showed evidence for association with SZ.	Positive

Gene relationship with MDD

View in gBrowse

Region: chr13:51584455..51767707 View in gBrowse