Gene Report

Basic Info
Approved Symbol JAM3
Symbol Alias JAM-C, JAMC
Approved Name junctional adhesion molecule 3
Location 11q25
Position chr11:134068925-134152001, 1
External Links HGNC: 15532
Entrez Gene: 83700
Ensembl: ENSG00000166086
UCSC: uc001qhb.3
No. of Studies 2 (Positive: 1; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Ollila, H. M.,2009 SNP: rs10791345 It showed no evidence for association with BPI in our study. Negative Comment on Study
Moskvina, V.,2009 In BD:Smallest P-value per gene=0.00245, Product of P truncation <=0.01=0.00196, Product of P truncation <=0.001=0.00444. It showed evidence for association with BD. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 29)

GO terms by PBA (count: 3)

GO terms by database search (count: 26)

Gene related KEGG pathways (count: 4)

KEGG pathways by PBA (count: 2)

KEGG pathways by database search (count: 2)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 6)

Related other genetic factors
Gene related SNPs (count: 10)

Literature-origin SNPs (count: 1)

LD-proxies (count: 9)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 0)

Gene relationship with MDD

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Region: chr11:134068925..134152001 View in gBrowse
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